Molecular Oncology Inc

Address

19 Firstfield Rd
Gaithersburg, MD, 20878

Information

DUNS:
# of Employees: N/A

Ownership Information

Hubzone Owned: N
Socially and Economically Disadvantaged: N
Woman Owned: N

Award Charts




Award Listing

  1. ANTIBODIES TO HUMAN TYPE IV COLLAGENASE AND ITS INHIBITOR

    Amount: $49,999.00

    THE DEGRADATION OF BASEMENT MEMBRANE IS IMPORTANT FOR LEUKOCYTE MIGRATION, TISSUE REMODELING, WOUND HEALING, ANGIOGENESIS AND TUMOR INVASION. TYPE IV COLLAGEN, THE MAJOR COMPONENT OF BASEM NT MEMBRANE ...

    SBIRPhase I1992Department of Health and Human Services
  2. EXPRESSION OF ENZYMES AND INHIBITORS OF METASTASIS

    Amount: $50,000.00

    DEGRADATION OF COLLAGEN IV IN BASEMENT MEMBRANES HAS BEEN IMPLICATED IN THE PATHOGENESIS OF METASTASIS, AND IN THE PROCESS OF ANGIOGENESIS. THE 72 KD AND THE 92 KD TYPE IV COLLAGENASES ARE METALLOPROT ...

    SBIRPhase I1992Department of Health and Human Services
  3. BISPECIFIC SINGLE CHAIN ANTIBODY VARIABLE REGIONS

    Amount: $50,000.00

    MOLECULES THAT CONTAIN TWO DISTINCT ANTIGEN BINDING DOMAINS, BISPECIFIC ANTIBODIES, HAVE SHOWN PROMISE AS MOVEL ANTI-CANCER THERAPEUTIC AGENTS. TO DATTE, SUCH BISPECIFIC ANTIBODIES HAVE BEEN PREPARED ...

    SBIRPhase I1992Department of Health and Human Services
  4. MECHANISTIC APPRAOCH FOR DESIGN OF ANTI-METASTASIS DRUGS

    Amount: $50,000.00

    THE GOAL OF THE PROJECT IS TO DEVELOP NEW ORGANIC COMPOUNDS THAT HAVE SPECIFIC ANTI-METASTATIC ACTIVITY FOR USE IN ADJUVANT TREATMENT OF CANCER PATIENTS TO INHIBIT OR DELAY THE DEVELOPMENT OF METASTAT ...

    SBIRPhase I1992Department of Health and Human Services
  5. SYNTHETIC VACCINES: TEST OF CONCEPTS AND APPLICATION TO RIFT VALLEY FEVER VIRUS

    Amount: $396,732.00

    USE OF SYNTHETIC PEPTIDES, COMPRISING BOTH B AND T CELL DETERMINANTS, IS BEING CONSIDERED A VIABLE APPROACH TO VACCINE DEVELOPMENT. WE WILL EXPLORE THE SUITABILITY OF THIS STRATEGY EMPLOYING RIFT VALL ...

    SBIRPhase II1991Army Department of Defense
  6. ANTIBODIES TO HUMAN NM23: A POTENTIAL MARKER OF MALIGNANCY

    Amount: $500,000.00

    FOR MANY TYPES OF CANCER, PATIENT MORBIDITY-AND ULTIMATELY MORTALITY-IS DUE TO THE DEVELOPMENT OF METASTATIC LESIONS. EXPERIMENTAL EVIDENCE SUGGESTS THAT TUMORS CAN INHERENTLY DIFFER IN THEIR ABILITY ...

    SBIRPhase II1991Department of Health and Human Services
  7. LS-MET-1, A HIGHLY METASTATIC HUMAN CARCINOMA CELL LINE

    Amount: $50,000.00

    METASTASIS FROM TUMORS OF EPITHELIAL ORIGIN SUCH AS THE LUNG, COLON, BREAST, AND PROSTATE CONSTITUTE THE CAUSE OF THE MAJORITY OF CANCER RELATED DEATHS. THERE EXIST FEW EXPERIMENTAL SYSTEMS SUITABLE F ...

    SBIRPhase I1991Department of Health and Human Services
  8. HUMAN COLLAGENASE IV AND ITS INHIBITORS

    Amount: $50,000.00

    THE DEGRADATION OF THE COLLAGEN TYPE IV NETWORK IN BASEMENT MEMBRANES IS A CRITICAL EVENT IN MANY NORMAL AND PATHOLOGICAL CONDITIONS INCLUDING TISSUE REMODELLING, WOUND HEALING, TUMOR CELL METASTASIS, ...

    SBIRPhase I1991Department of Health and Human Services
  9. DOMAIN-SPECIFIC ANTIBODIES TO HUMAN ERB-2/NEU PROTEIN

    Amount: $447,480.00

    IN 20 TO 40 PERCENT OF HUMAN BREAST CANCERS, THE ERBB-2 OR NEU GENE IS AMPLIFIED, LEADING TO MRNA AND PROTEIN OVEREXPRESSION. THIS OVEREXPRESSION IS LIKELY TO BE INVOLVED IN EITHER THE INITIATION OR P ...

    SBIRPhase II1990Department of Health and Human Services
  10. ANTIBODIES TO HUMAN NM23: A POTENTIAL MARKER OF MALIGNANCY

    Amount: $50,000.00

    N/A

    SBIRPhase I1990Department of Health and Human Services

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