REACTION BIOLOGY CORPORATION

Basic Information

ONE GREAT VALLEY PARKWAY
MALVERN, PA, 19355-1423

Company Profile

n/a

Additional Details

Field Value
DUNS: 611741799
Hubzone Owned: N
Socially and Economically Disadvantaged: N
Woman Owned: N
Number of Employees: n/a


  1. Fluorescence Polarization Probes for Universal Coverage of the Human Bromodomains

    Amount: $222,902.00

    DESCRIPTION provided by applicant Post translational modification PTM of the lysines and other residues in the N terminal tails of histones are known to have profound effects on the structure and ...

    SBIR Phase I 2015 Department of Health and Human Services National Institutes of Health
  2. Probe Development for Bromodomains Networks

    Amount: $290,439.00

    DESCRIPTION provided by applicant Epigenetic regulation of gene expression is a highly dynamic and reversible process essential to normal cellular function However it also contributes to human di ...

    SBIR Phase I 2015 Department of Health and Human Services National Institutes of Health
  3. Epigenetics Probes: Production of histone modifying enzymes and identification o

    Amount: $287,650.00

    DESCRIPTION (provided by applicant): Production of histone modifying enzymes and identification of chemical probes for epigenetic discovery Genomic function is the major factor in the most common dise ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Chemoprotectants for Head-Neck Therapeutics

    Amount: $1,402,563.00

    DESCRIPTION (provided by applicant): Chemoprotectants for Head-Neck Therapeutics Oral mucositis occurs as a major dose-limiting and complicating side effect of chemotherapy, radiotherapy, or combined ...

    SBIR Phase II 2011 Department of Health and Human Services
  5. Methyltransferase Drug Discovery

    Amount: $1,203,230.00

    DESCRIPTION (provided by applicant): Chromatin assembly and structure is highly regulated during DNA replication, gene expression, and progression through the cell cycle. Dysfunctions of epigenetic fa ...

    SBIR Phase II 2010 Department of Health and Human Services
  6. Methyltransferase Drug Discovery

    Amount: $170,727.00

    DESCRIPTION (provided by applicant): Chromatin assembly and structure is highly regulated during DNA replication, gene expression, and progression through the cell cycle. Dysfunction of epigenetic fac ...

    SBIR Phase I 2009 Department of Health and Human Services
  7. Chemoprotectants for Head-Neck Therapeutics

    Amount: $252,860.00

    DESCRIPTION (provided by applicant): Chemoprotectants for Head-Neck Therapeutics Oral mucositis occurs as a major dose-limiting and complicating side effect of chemotherapy, radiotherapy, or combined ...

    SBIR Phase I 2009 Department of Health and Human Services
  8. High throughput ELISA chip for drug toxicity screening

    Amount: $463,506.00

    DESCRIPTION (provided by applicant): High throughput ELISA chip for drug toxicity screening Summary Adverse drug metabolism, drug-drug interactions, and direct toxicity effects have caused numerous dr ...

    SBIR Phase II 2007 Department of Health and Human Services
  9. Kinome Drug Bioassay Platform

    Amount: $947,589.00

    DESCRIPTION (provided by applicant): Reaction Biology Corporation (RBC) has developed an extremely low cost nanoliter reaction microarray to serve various drug discovery needs for high throughput scre ...

    SBIR Phase II 2006 Department of Health and Human Services
  10. Enzyme Assay Chips for Apoptosis Discovery

    Amount: $750,869.00

    DESCRIPTION (provided by applicant): Reaction Biology Corporation has developed an extremely low cost nanoliter reaction microarrays to serve markets for ultra high throughput screening (uHTS) drug d ...

    SBIR Phase II 2005 Department of Health and Human Services

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