Three energy sources that will work in a cold, dark, static environment

Award Information
Agency:
Department of Defense
Amount:
$99,999.00
Program:
SBIR
Contract:
DAMD17-02-C-0007
Solitcitation Year:
N/A
Solicitation Number:
N/A
Branch:
Office of the Secretary of Defense
Award Year:
2001
Phase:
Phase I
Agency Tracking Number:
O012-0187
Solicitation Topic Code:
N/A
Small Business Information
NANOSONIC, INC.
P.O. Box 618, Christiansburg, VA, 24068
Hubzone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Duns:
008963758
Principal Investigator
 Jeffrey Mecham
 Research Scientist
 (540) 953-1785
 jbmecham@nanosonic.com
Business Contact
 Richard Claus
Title: President
Phone: (540) 953-1785
Email: roclaus@nanosonic.com
Research Institution
N/A
Abstract
The purpose of the proposed OSD Phase I program is to develop and commercialize novel tissue solders based on a biodegradable copolymer system that contains a controlled degree of acrylate-terminated photoactive branch sites. This will result in a processthat, with the addition of a biocompatible and non-toxic photosensitizer/electron donor initiating system, will rapidly cure from a viscous liquid to a tough ductile polymer in a matter of milliseconds. This reaction occurs with a minimal heat ofpolymerization in an oxygen-containing aqueous environment at physiological pH. The free-radical cure reaction is easily triggered by applying a filtered and focused light beam via optical fiber from a source with a broad wavelength range to the syntheticsolder (polymer/initiator) formulation. Utilization of a specified fiber type allows control of this range such that the surrounding tissue is not subjected to potentially damaging wavelengths that are frequently a problem associated with laser systems.Addition of a light sensitive dye to the formulation serves as a visual cue to the surgeon as an indicator of cure conversion. As the dye changes color, visual feedback is provided to the surgeon indicating the completion of the procedure. The purpose ofthe proposed OSD Phase I program is to develop and commercialize novel tissue solders based on a biodegradable copolymer system that contains a controlled degree of acrylate-terminated photoactive branch sites. This will result in a process that, with theaddition of a biocompatible and non-toxic photosensitizer/electron donor initiating system, will rapidly cure from a viscous liquid to a tough ductile polymer in a matter of milliseconds. This reaction occurs with a minimal heat of polymerization in anoxygen-containing aqueous environment at physiological pH. The free-radical cure reaction is easily triggered by applying a filtered and focused light beam via optical fiber from a source with a broad wavelength range to the synthetic solder(polymer/initiator) formulation. Utilization of a specified fiber type allows control of this range such that the surrounding tissue is not subjected to potentially damaging wavelengths that are frequently a problem associated with laser systems. Additionof a light sensitive dye to the formulation serves as a visual cue to the surgeon as an indicator of cure conversion. As the dye changes color, visual feedback is provided to the surgeon indicating the completion of the procedure.

* information listed above is at the time of submission.

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