INSECT ANTIFEEDANT SALANNIN, A MODEL FOR A NEW COMMERCIAL INSECT CONTROL AGENT

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$50,000.00
Award Year:
1987
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
6869
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Native Plants Inc
417 Wakara Way, Salt Lake City, UT, 84108
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
DR JAMES A KLOCKE
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
SALANNIN (C34H4O9) IS A PLANT TETRANORTRITERPENOID OCCURRINGIN TWO SPECIES IN THE MELIACEAE, AZADIRACHTA INDICA A. JUSS.(NEEM) AND MELIA DUBIA CAV. SALANNIN HAS BEEN SHOWN TO BE AN ANTIFEEDANT (FEEDING INHIBITOR) AGAINST SEVERAL SPECIES OF INSECT PEST, INCLUDING DIPTERANS (FLIES), LEPIDOPTERANS (CATERPILLARS), AND COLEOPTERANS (BEETLES). WE PLAN TO INVESTIGATE THE FEASIBILITY OF MODELING A NEW CHEMICAL INSECT CONTROL AGENT FROM SALANNIN. THERE IS A NEED FOR NEWCHEMICALS, ESPECIALLY BIORATIONAL CHEMICALS SUCH AS ANTIFEEDANTS, WHICH ARE EFFICACIOUS IN INSECT CONTROL, BUT WHICH ARE ALSO SAFE TO USE IN THE ENVIRONMENT AND WHICH ARE AMENABLE FOR USE IN INTEGRATED PEST CONTROL. NPI WILL QUANTITATE SALANNIN IN NEEM SEEDS OBTAINED FROM VARIOUS GEOGRAPHICAL LOCATIONS AND WE WILL ISOLATE (GRAM-SCALE) IT FROM THE RICHEST NEEM SEED SOURCE. DERIVATIVES WILL BE MADE OF THE ISOLATED SALANNIN AND TESTEDFOR ANTIFEEDANT ACTIVITY AGAINST LEPTINOTARSA DECEMLINEATA (SAY) (COLORADO POTATO BEETLE), HELIOTHIS VIRESCENS (FABR.) (TOBACCO BUDWORM), AND SCHIZAPHIS GRAMINUM (RODANI) (GREEMBUG) AND FOR SYSTEMIC ACTIVITY IN PLANTS. THE RESULT WILL GUIDE SYNTHETIC, FORMULATION, AND GREENHOUSE STUDIES IN PHASE II.

* information listed above is at the time of submission.

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