NAVIGEN, INC.

Company Information

Company Name
NAVIGEN, INC.
Address
383 Colorow Drive
SALT LAKE CITY, UT, 84108-1201
Phone
n/a
URL
http://www.nvgn.com
DUNS
792046224
Number of Employees
19
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$3,371,415.00
10
SBIR Phase II
$6,894,796.00
4
Chart code to be here

Award List

  1. Novel Therapeutic Approach to Acute Lung Injury

    Amount: $1,121,436.00

    DESCRIPTION (provided by applicant): In our Phase 1 application, we described an endothelial specific receptor, Robo4, that is expressed in mature vessels and is upregulated following endothelial inju ...

    SBIR Phase II 2010 Department of Health and Human Services
  2. SLIT2N for the treatment of influenza-induced acute respiratory distress

    Amount: $591,856.00

    DESCRIPTION (provided by applicant): Influenza infection leads to a cytokine storm as the host's immune system fights the virus. This combination of immunity factors has the unfortunate side effect of ...

    SBIR Phase I 2010 Department of Health and Human Services
  3. Novel Therapeutic Approach to Acute Lung Injury

    Amount: $147,660.00

    DESCRIPTION (provided by applicant): Navigen Pharmaceutical will develop a novel class of protein therapies for treating acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). This work i ...

    SBIR Phase I 2008 Department of Health and Human Services
  4. Inhibiting pathologic angiogenesis and vascular leak in the eye.

    Amount: $140,000.00

    DESCRIPTION (provided by applicant): A Navigen founder, Dean Li, MD, PhD, has identified a novel endothelial receptor, Robo4. Robo4 is highly expressed in the retinal endothelium, and activation of t ...

    SBIR Phase I 2008 Department of Health and Human Services
  5. Targeting HTRA 1 for the Treatment of Age Related Macular Degeneration

    Amount: $146,999.00

    DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is the most common cause of visual impairment of the elderly in developed countries. Despite its prevalence with the aging p ...

    SBIR Phase I 2008 Department of Health and Human Services
  6. Anti-HTRA1 Therapy For AMD

    Amount: $1,270,716.00

    DESCRIPTION (provided by applicant): In our Phase I application, we proposed that blocking HTRA1 with antibodies might be an effective strategy for treating age related macular degeneration. We tested ...

    SBIR Phase II 2009 Department of Health and Human Services
  7. Novel Therapeutic Approach for Sepsis: Blocking the Vascular Response to Cytokine

    Amount: $557,531.00

    DESCRIPTION (provided by applicant): In the United States alone, sepsis affects approximately 700,000 patients and leads to death of over 210,000 people per year. Sepsis is a clinical syndrome that re ...

    SBIR Phase I 2011 Department of Health and Human Services
  8. Therapeutic D-peptide Inhibitor of HIV entry

    Amount: $299,392.00

    DESCRIPTION (provided by applicant): HIV/AIDS remains a formidable global epidemic with 33 million infections worldwide, including over 1 million patients in the US. In 2008, there were 2.7 million ne ...

    SBIR Phase I 2011 Department of Health and Human Services
  9. Protease-resistant D-peptide inhibitors of RSV entry

    Amount: $592,068.00

    DESCRIPTION (provided by applicant): Respiratory syncytial virus (RSV) is the major cause of severe lower respiratory tract infections in children and infants, affecting an estimated 64 million people ...

    SBIR Phase I 2012 Department of Health and Human Services
  10. Protease-resistant D-peptide Inhibitors of Ebola Virus Entry

    Amount: $600,000.00

    DESCRIPTION (provided by applicant): Ebola virus (EboV) is a filovirus that causes a highly deadly hemorrhagic fever in humans and non-human primates. Since its discovery in central Africa in 1976, th ...

    SBIR Phase I 2012 Department of Health and Human Services

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