SBIR Phase II: Development and Manufacture of High-Density Plate Washer

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$500,000.00
Award Year:
2005
Program:
SBIR
Phase:
Phase II
Contract:
0450448
Award Id:
63315
Agency Tracking Number:
0319656
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
POB 64326, Tucson, AZ, 85718
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Richard Kris
Dr
(520) 270-5209
richardkris@earthlink.net
Business Contact:
Richard Kris
Dr
(520) 270-5209
richardkris@earthlink.net
Research Institute:
n/a
Abstract
This Small Business Innovation Research (SBIR) Phase II project aims to develop a plate washer capable of washing very high-density plates, such as 1536 well plates, for ELISA and high-throughput screening assays. Currently, there are automated plate washers for 96 and 384 well plates, but there are none available for plates with ultra-high density. This is because currently available washer technology, employing a nozzle system, cannot be made reliable enough to allow dispense and aspirate nozzles to properly reach within each of the many, very small wells, and because the thin nozzles needed can get easily clogged using many standard buffers. In contrast, the proposed system uses a steady stream or sheet of solution, making the system less likely to clog. The commercial application of this project will be to allow use of high-throughput screening assays by industrial and academic researchers involved in genomics and drug discovery research. The proposed technology will enable additional use of fluorescent chemical compounds, that typically require a wash step to remove interfering substances, for screening.

* information listed above is at the time of submission.

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