Polymer Coatings for Prevention of Bacterial Contamination of Dental Waterlines

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$99,073.00
Award Year:
2006
Program:
SBIR
Phase:
Phase I
Contract:
1R43DE017827-01
Award Id:
79803
Agency Tracking Number:
DE017827
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
NERITES CORPORATION, 525 SCIENCE DR., MADISON, WI, 53719
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
JEFFREY DALSIN
(608) 443-2443
jdalsin@nerites.com
Business Contact:
THOMAS MOZER
(608) 443-2440
TMOZER@NERITES.COM
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): Polymer Coatings for Prevention of Bacterial Contamination in Dental Waterlines Copious amounts of water are used for rinsing and cooling purposes in restorative and surgical dental procedures. Bacterial fouling of dental unit waterlines that deliver this water is a persistent problem in clinical dentistry and dental surgery. While the risk of bacterial infection is slight in most healthy patients, those patients with compromised immune systems due to disease or drug therapy are at elevated risk. Additionally, dental healthcare professionals are subjected to chronic exposure to contaminated water and aerosols generated from the dental unit. Existing approaches to combat bacterial contamination and biofilm formation are typically not effective in reducing bacteria counts to levels recommended by the American Dental Association. Finally, the majority of the existing approaches rely on healthcare workers to adhere to specific maintenance schedules that, if not followed, render the approaches largely ineffective. New approaches to dental waterline antifouling that would significantly reduce or eliminate the need for routine decontamination maintenance are of great interest to the dental healthcare community. Surface coatings which repel bacterial attachment on dental waterlines and biofilm formation would significantly reduce these health risks. If bacteria cannot attach to the surfaces of dental waterlines, they will not be able to form biofilms to allow them to reproduce in large numbers and contaminate the water supply. Coatings will be developed and evaluated that prevent bacterial attachment to surfaces of materials commonly used in the manufacture of dental waterlines. In stage one, surface coatings will be developed that adhere tightly to these materials and form coatings covering these surfaces. In stage two, these coated surfaces will be evaluated for their ability to prevent bacterial attachment to the surfaces of these materials under both static and dynamic conditions. In future research, the coatings that have been developed will be evaluated for their effective on actual dental unit waterlines. Project Summary/Abstract (Description) Page 7 Principal Investigator/Program Director (Last, first, middle): Dalsin, Jeffrey, L. Project Narrative Polymer Coatings for Prevention of Bacterial Contamination in Dental Waterlines Copious amounts of water are used for rinsing and cooling purposes in restorative and surgical dental procedures. Bacterial contamination of these water supplies is a chronic and serious problem. Coatings for waterlines that are designed to prevent bacterial growth would largely prevent this problem, thereby reducing health-related risks to both patients and dental care workers.

* information listed above is at the time of submission.

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