DETECTION OF LARGE MOLECULAR WEIGHT TOXINS

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$50,000.00
Award Year:
1990
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
12737
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
New Horizons Diagnostics
9110 Red Branch Rd, Columbia, MD, 21045
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
David Miller
(301) 992-9357
Business Contact:
() -
Research Institution:
n/a
Abstract
NEW HORIZONS DIAGNOSTICS (NHD) HAS SEVERAL PATENTS FOR NOVEL RAPID AND SIMPLE LIGAND-RECEPTOR ASSAYS. NHD'S GOAL HAS BEEN TO PRODUCE ASSAYS SIMPLE ENOUGH TO BE PERFORMED BY UNSKILLED OR UNTRAINED INDIVIDUALS WITHOUT ANY EQUIPMENT NEEDS. THROUGH THE COMMERCIAL INTRODUCTION OF THE DIRECT GROUP A STREP SMART (SENSITIVIE MEMBRANE ANTIGEN RAPID TEST), NHD HAS PROVEN ITSELF TO BE IN THE FOREFRONT OF RAPID IMMUNO-DIAGNOSTIC TECHNOLOGY. THE GROUP A STREP SMART CAN DETECT AS FEW AS 2000 STREPTOCOCOCCI FROM A SWAB IN LESS THAN 7 MINUTES. IN CLINICAL EVALUATION, THE SMART HAS PROVEN TO BE MORE SIMPLE AND SIGNIFICANTLY MORE SENSITIVE THAN LATEX AGGLUTINATION, ELISA-MEMBRNE, OR LIPOSOME-MEMBRANE BASED GROUP A STREP ASSAYS. THE SMART PROCEDURE USES A SWAB FOR SAMPLE COLLECTION, WHICH IS REACTED WITH A METAL SOL LABELED ANTIBODY ON A MEMBRANE, APPEARING AS A PINK TO PURPLE SPOT. THE SMART KIT IS STORES AND PERFORMED AT ROOM TEMPERATURES AND THEREFORE IS CAPABLE OF BEING USED AS A FIELD DETECTOR/IDENTIFICATION KIT. IN THE PHASE I PROGRAM, A PROTOTYPE RAPID AND SIMPLE ASSAY IN THE SMART FORMAT WILL BE PROVIDED TO DETECT UP TO THREE LARGE MOLECULAR WEIGHT TOXINS, USING GOBERNMENT-FURNISHED REAGENTS.

* information listed above is at the time of submission.

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