TEST KIT DEVELOPMENT FOR AGENTS OF BIOLOGICAL ORIGIN

Award Information
Agency:
Department of Defense
Branch
Navy
Amount:
$485,358.00
Award Year:
1992
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Award Id:
12738
Agency Tracking Number:
12738
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
9110 Red Branch Rd, Columbia, MD, 21045
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
David Bernstein
(301) 992-9357
Business Contact:
() -
Research Institute:
n/a
Abstract
NEW HORIZONS DIAGNOSTICS (NHD) HAS SEVERAL PATENTS FOR NOVEL RAPID AND SIMPLE LIGAND-RECEPTOR ASSAYS. NHD'S GOAL HAS BEEN TO PRODUCE ASSAYS SIMPLE ENOUGH TO BE PERFORMED BY UNSKILLED OR UNTRAINED INDIVIDUALS WITHOUT ANY EQUIPMENT NEEDS. THROUGH THE COMMERCIAL INTRODUCTION OF THE DIRECT GROUP A STREP SMART (SENSITIVE MEMBRANE ANTIGEN RAPID TEST), NHD HAS PROVEN ITSELF TO BE IN THE FOREFRONT OF RAPID IMMUNO-DIAGNOSTIC TECHNOLOGY. THE GROUP A STREP SMART CAN DETECT AS FEW AS 2000 STREPTOCOCOCCI FROM A SWAB IN LESS THAN 7 MINUTES. IN CLINICAL EVALUATION, THE SMART HAS PROVEN TO BE MORE SIMPLE AND SIGNIFICANTLY MORE SENSITIVE THAN LATEX AGGLUTINATION, ELISA-MEMBRANE, OR LIPOSOME-MEMBRANE BASED GROUP A STREP ASSAYS. THE SMART PROCEDURE USES A SWAB FOR SAMPLE COLLECTION, WHICH IS REACTED WITH A METAL SOL LABELED ANTIBODY AND THEN PLACED IN A SMART DEVICE WHEREIN ANY IMMUNOCOMPLEXES FORMED ARE CAPTURED ON A MEMBRANE, APPEARING AS A PINK TO PURPLE SPOT. THE SMART KIT IS STORED AND PERFORMED AT ROOM TEMPERATURES AND THEREFORE IS CAPABLE OF BEING USED AS A FIELD DETECTION/IDENTIFICATION KIT. IN THE PHASE I PROGRAM, A PROTOTYPE RAPID AND SIMPLE ASSAY IN THE SMART FORMAT WILL BE DEVELOPED FOR 2 PATHOGENS OR TOXINS OF INTEREST TO THE CONTRACTOR. THE SPECIFIC ANTIBODIES AND ANTIGEN WOULD BE PROVIDED BY THE CONTRACTOR. WE WILL ALSO EXAMINE THE FEASIBILITY OF TESTING TWO AGENTS FROM A SINGLE SWAB SIMULTANEOUSLY WITHIN A SINGLE SMART DEVICE.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government