IMAGE PROCESSING APPLIED TO 2D NMR SPECTROSCOPY

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$49,200.00
Award Year:
1989
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
11381
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
New Methods Research Inc
719 E Genesee St, Syracuse, NY, 13210
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
THE OBJECTIVE OF THIS PROJECT IS TO APPLY THE METHODS OF IMAGE PROCESSING TO ENHANCE THE QUALITY OF TWO-DIMENSIONAL (2-D) FT NUCLEAR MAGNETIC RESONANCE (NMR) SPECTRA. FILTERING, DECONVOLUTION, AND OTHER RECONSTRUCTION ALGORITHMS WILL BE DEVELOPED SPECIFICALLY TO WORK WITH COMPLEX 2-D NMR SPECTRA, ANALOGOUS TO BUT DIFFERENT FROM CONVENTIONAL IMAGES. SYMMETRY AND OTHER RELATIONSHIPS AND EXPERTISE WILL BE INCORPORATED INTO THIS APPROACH. THE SOFTWARE DEVELOPED IN THIS PROJECT WILL BE WIDELY ACCESSIBLE THROUGH LINKAGE WITH AN EXISTING COMPUTER PROGRAM, NMR2. FURTHER, THE PROBLEMS OF PRIMARY ACQUISITIONOF 2-D DATA ARE EASILY MET BY EXISTING ROUTINES THAT TRANSLATE/ACQUIRE NMR DATA FROM BRUKER, GE, VARIAN, JEOL, AND CHEMAGNETICS INSTRUMENTS, AS WELL AS SEVERAL IMAGERS.

* information listed above is at the time of submission.

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