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Spatial genomics analysis of tumor samples

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R44CA285121-01
Agency Tracking Number: R44CA285121
Amount: $998,481.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: 102
Solicitation Number: PA22-176
Timeline
Solicitation Year: 2022
Award Year: 2023
Award Start Date (Proposal Award Date): 2023-09-01
Award End Date (Contract End Date): 2025-08-31
Small Business Information
145 Vista Ave
Pasadena, CA 91107
United States
DUNS: 080426411
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 KIRSTEN FRIEDA
 (626) 314-3460
 kfrieda@spatialgenomics.com
Business Contact
 KIRSTEN FRIEDA
Phone: (626) 314-3460
Email: kfrieda@spatialgenomics.com
Research Institution
N/A
Abstract

SUMMARY
Imaging the tumor microenvironment (TME) is key to understanding tumor growth, disease
progression and therapy options. The TME often consists of a complex neighborhood of diverse
populations of immune cells, fibroblasts, and tumors cells. Little is known about the “geography”
of the tumors and the spatial organization of the distinct cell types. The ability to rapidly identify
different cell types and tumor subtypes using molecular markers will be transformative for cancer
diagnostics.
At Spatial Genomics, we are commercializing technology that allows transcript profiling in tumor
samples. With this technology, cell types in situ and spatial organizations can be directly identified
and visualized in tumor tissue slices. These capabilities provide a powerful tool for examining the
different cell types and their interactions in the tumor microenvironment. In this proposal, we will
develop the reagents, instrumentation, and the associated software that will allow researchers to
perform spatial mapping experiments in tumor slices.

* Information listed above is at the time of submission. *

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