PROCESS FOR CLONING DIFFERENTIALLY EXPRESSED GENES

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$49,919.00
Award Year:
1992
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
19257
Agency Tracking Number:
19257
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
597 Science Drive, Madison, WI, 53711
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Robert C Mierendorf
(608) 238-6110
Business Contact:
() -
Research Institute:
n/a
Abstract
THE RESEARCH WOULD INVESTIGATE THE FEASIBILITY OF A METHOD FOR DIRECT ISOLATION AND CLONING OF GENES ASSOCIATED WITH STATES OF DISEASE, CELL DIFFERENTIATION, OR METABOLIC INDUCTION. PHASE I STUDIES WILL FOCUS ON STEPS IN THE PROCESS THAT CURRENTLY LIMIT THE WIDESPREAD USE OF SUBTRACTIVE NUCLEIC ACID HYBRIDIZATION AS A MEANS OF ISOLATING THE TARGET GENES. IN PHASE II THIS TECHNOLOGY WILL BE INTEGRATED AND OPTIMIZED TO ALLOW THE CLONING OF ANY GENE THAT IS ACTIVE IN ONE CELL TYPE BUT NOT ANOTHER.

* information listed above is at the time of submission.

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