ONCOGENE SCIENCE, INC.

Company Information

Company Name
ONCOGENE SCIENCE, INC.
Address
106 CHARLES LINBERGH BLVD
Uniondale, NY, 11553
Phone
n/a
URL
n/a
DUNS
n/a
Number of Employees
n/a
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$2,715,413.00
47
SBIR Phase II
$7,627,997.00
15
Chart code to be here

Award List

  1. DNA PROBES FOR DETECTION OF CHROMOSOMAL TRANSLOCATIONS

    Amount: $250,000.00

    A SPECIFIC CHROMOSOMAL TRANSLOCATION, THE PHILADELPHIA TRANSLOCATION, IS CHARACTERISTIC OF OVER 96% OF PATIENTS WITH CHRONIC MYELOCYTIC LEUKEMIA. THIS TRANSLOCATION INVOLVES THE TRANSFER OF THE C-ABL ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. DNA PROBE ASSAY FOR THE PHILADELPHIA TRANSLOCATION

    Amount: $500,000.00

    LEUKEMIC CELLS OF APPROXIMATELY 96 PERCENT OF PATIENTS WITH CHRONIC MYELOGENOUS LEUKEMIA (CML) AND 10 TO 25 PERCENT OF ACUTE LYMPHOCYTIC LEUKEMIA (ALL) PATIENTS ARE CHARACTERIZED BY A MARKER CHROMOSOM ...

    SBIR Phase II 1989 Department of Health and Human Services
  3. IMMUNOLOGIC ASSAY FOR THE PHILADELPHIA TRANSLOCATION

    Amount: $492,000.00

    OVER 96 PERCENT OF ALL CHRONIC MYELOGENOUS LEUKEMIA (CML) AND 17 TO 25 PERCENT OF ALL ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS HAVE A PHILADELPHIA (PH') CHROMOSOME IN THEIR LEUKEMIC CELLS. AS THE PRESENC ...

    SBIR Phase II 1988 Department of Health and Human Services
  4. RECEPTOR

    Amount: $45,000.00

    THE EPIDERMAL GROWTH FACTOR RECEPTOR IS A 170,000 DALTON GLYCOPROTEIN COMPOSED OF THREE DOMAINS. THE CELL SURFACE DOMAIN BINDS EPIDERMAL GROWTH FACTOR (EGF) AND A LOW MOLECULAR WEIGHT, TUMOR-SPECIFIC ...

    SBIR Phase I 1986 Department of Health and Human Services
  5. PROTEIN KINASE C IS ACTIVATED BY TUMOR PROMOTORS AND THERE IS STRONG EVIDENCE THAT IT ACTUALLY MEDIATES TUMOR PROMOTION.

    Amount: $50,000.00

    PROTEIN KINASE C IS ACTIVATED BY TUMOR PROMOTORS AND THERE IS STRONG EVIDENCE THAT IT ACTUALLY MEDIATES TUMOR PROMOTION. ACTIVATED PROTEIN KINASE C PHOSPHORYLATES THE EPIDERMAL GROWTH FACTOR RECEPTOR ...

    SBIR Phase I 1986 Department of Health and Human Services
  6. PURIFICATION OF HUMAN PLATELET DERIVED GROWTH FACTOR RECEPTOR

    Amount: $50,000.00

    THE TWO MOST PREVALENT CAUSES OF DEATH IN WESTERN CIVILIZATION ARE MYOCARDIAL AND CEREBRAL INFARCATIONS. THESE CONDITIONS ARE PRIMARILY THE RESULT OF ATHEROSCLEROTICLESIONS WHICH THE BLOOD VESSELS SUP ...

    SBIR Phase I 1988 Department of Health and Human Services
  7. IMMUNOASSAY TO MONITOR EGF LEVELS IN HUMAN PREGNANCY

    Amount: $50,000.00

    EPIDERMAL GROWTH FACTOR (EGF) IS A POTENT MITOGEN FOR A VARIETY OF CELL TYPES BOTH IN VITRO AND IN VIVO. RECENT STUDIES HAVE SUGGESTED THAT EGF MAY PLAY A ROLE IN THE MAINTENANCE OF NORMAL PREGNANCY I ...

    SBIR Phase I 1988 Department of Health and Human Services
  8. CHARACTERIZATION OF SRC KINASE ACTIVATION IN COLON TUMORS.

    Amount: $50,000.00

    A RECENT STUDY HAS REPORTED ELEVATED LEVELS OF P60(C-SRC) PROTEIN-TYROSINE KINASE SPECIFIC ACTIVITY IN 100% OF HUMAN COLON CARCINOMA TUMOR TISSUES AND CELL LINES EXAMINED (1). FOUR MECHANISMS COULD AC ...

    SBIR Phase I 1988 Department of Health and Human Services
  9. YEAST MRNA 3' END FORMATION AS AN ANTIFUNGAL DRUG TARGET

    Amount: $49,354.00

    THE FORMATION OF POLYADENYLATED 3'-TERMINI IS AN ESSENTIAL STEP IN THE BIOGENESIS OF EUKARYOTIC MRNA. IN VERTEBRATES, THE CONSENSUS AAUAAA AND OTHER SEQUENCES HAVE BEEN IDENTIFIED AS REQUIREMENTS FOR ...

    SBIR Phase I 1989 Department of Health and Human Services
  10. EUKARYOTIC EXPRESSION OF TRANSFORMING GROWTH FACTOR B3

    Amount: $184,345.00

    TRANSFORMING GROWTH FACTORS TYPE BETA (TGF-BETA'S) ARE PROTEINS OF 25 KD DISULFIDE-LINKED HOMODIMERS AND HETERODIMERS THAT ACT TO CONTROL THE PROLIFERATION OF A VARIETY OF BOTH NORMAL AND TRANSFORMED ...

    SBIR Phase II 1991 Department of Health and Human Services

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