THE LONG-TERM GOAL OF THIS PROJECT IS THE DEVELOPMENT OF NEWTHERAPEUTIC STRATEGIES FOR THE CIRCUMVENTION OF DRUG RESISTANCE IN HUMAN NEOPLASMS.

Award Information
Agency:
Department of Health and Human Services
Amount:
$50,000.00
Program:
SBIR
Contract:
N/A
Solitcitation Year:
N/A
Solicitation Number:
N/A
Branch:
N/A
Award Year:
1986
Phase:
Phase I
Agency Tracking Number:
4768
Solicitation Topic Code:
N/A
Small Business Information
Oncotech Inc
2865 Atlantic Avenue, Suite 208, Long Beach, CA, 90806
Hubzone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Duns:
N/A
Principal Investigator
 ROBERT NAGOURNEY
 PRINCIPAL INVESTIGATOR
 (213) 424-0030
Business Contact
Phone: () -
Research Institution
N/A
Abstract
THE LONG-TERM GOAL OF THIS PROJECT IS THE DEVELOPMENT OF NEWTHERAPEUTIC STRATEGIES FOR THE CIRCUMVENTION OF DRUG RESISTANCE IN HUMAN NEOPLASMS. BY FIRST ESTABLISHING THE ABILITY OF THE DIFFERENTIAL STAINING CYTOTOXICITY ASSAY TO DETECT AND CIRCUMVENT DRUG RESISTANCE, THE PROJECT WILL LAY THE FOUNDATION FOR CLINICAL TRIALS DESIGNED TO APPLY INDIVIDUALIZED REGIMENS FOR THE EFFECTIVE TREATMENT OF REFRACTORY HUMAN MALIGNANCIES. THERAPIES WILL BE DESIGNED TO INCORPORATE SYNERGISTIC INTERACTIONS BETWEEN CYTOTOXIC AND NON-CYTOTOXIC AGENTS AND TO PROVIDE MAXIMAL PROTECTION TO NORMAL TISSUES. THE ULTIMATE GOAL WILL BE TO EXPAND THESE STUDIES INTO COOPERATIVE CLINICAL TRIALS AND TO REFINETHE TECHNIQUES AND EQUIPMENT USED FOR EVENTUAL DISSEMINATIONTO THE ONCOLOGIC COMMUNITY AT LARGE.

* information listed above is at the time of submission.

Agency Micro-sites

US Flag An Official Website of the United States Government