Handheld FRET-Aptamer Sensor for Agricultural Security

Award Information
Agency: Department of Agriculture
Branch: N/A
Contract: 2006-33610-16757
Agency Tracking Number: 2006-00138
Amount: $79,986.00
Phase: Phase I
Program: SBIR
Awards Year: 2006
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
4100 N.W. Loop 410 Suite 230, San Antonio, TX, 78229
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 John Bruno
 Senior Scientist
 (210) 732-0015
 john.bruno@otcorp.com
Business Contact
 William Henderson
Title: Chief Financial Officer
Phone: (210) 731-0000
Email: bhenders@otcorp.com
Research Institution
N/A
Abstract
America is highly vulnerable to agricultural bioterrorism. A successful attack could be devastating to the U.S. and world economy. Rapid detection of agricultural bioterrorism agents is critical to limiting or halting the spread of such disease agents. This project concerns development of a rapid, facile, one-step fluorescence resonance energy transfer (FRET)-aptamer assay and handheld sensor for foot-and-mouth disease (FMD) viruses (possible agricultural bioterrorism agents). Re-introduction of FMD into the U.S. could be limited or stopped by appropriate quarantine measures if detected on farms early in the process of spreading. The handheld sensor and FRET assays are intended to fulfill this need. If successful, this platform technology could be developed to detect other bioterrorism agents as well.

* Information listed above is at the time of submission. *

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