THE OBJECTIVE OF THE RESEARCH PROPOSED IN THIS APPLICATION IS TO DEVELOP AND TEST AN INSTRUMENT FOR IN VIVO MEASUREMENT OF ERYTHROCYTE VELOCITY AND MICROSPECTROPHOTOMETRY FOR OXYHEMOGLOBIN SATURATION DETERMINATION.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$37,400.00
Award Year:
1985
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
3255
Agency Tracking Number:
3255
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
8674 Jackson Square Place, Shreveport, LA, 71115
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
WINSTON O. JOHNSON
PRINCIPAL INVESTIGATOR
(318) 797-7970
Business Contact:
() -
Research Institution:
n/a
Abstract
THE OBJECTIVE OF THE RESEARCH PROPOSED IN THIS APPLICATION IS TO DEVELOP AND TEST AN INSTRUMENT FOR IN VIVO MEASUREMENT OF ERYTHROCYTE VELOCITY AND MICROSPECTROPHOTOMETRY FOR OXYHEMOGLOBIN SATURATION DETERMINATION. THE FIELD OF MICROCIRCULATORY RESEARCH CONTINUES TO BE DEPENDENT UPON THE DEVELOPMENT OF SPECIALIZED INSTRUMENTATION FOR MEASUREMENT OF MICROVASCULAR HEMODYNAMIC VARIABLES. THE COMMERCIAL AVAILABILITY OF AN INSTRUMENT WHICH IS ACCURATE, EASY TO IMPLEMENT, AND OF RELATIVELY LOW COST FOR MEASUREMENT OF RED BLOOD CELL VELOCITY AND OXYHEMOGLOBIN SATURATION SHOULD SIGNIFICANTLY ENHANCE THE BASIC SCIENCE AND CLINICAL RESEARCH POTENTIAL IN THIS FIELD. THE OBJECTIVES OF PHASE I ARE THREEFOLD: 1. TO MODIFY THE VELOCIMETER FOR DETECTION OF THE DIRECTION OF BLOOD FLOW,2. 3. THE LONG-TERM OBJECTIVES OF PHASE II ARE TO FURTHER DEVELOP THE VELOCIMETER FOR BOTH CLINICAL AND RESEARCH APPLICATIONS, EMPHASIZING SIMPLICITY AND ACCURACY OF OPERATION, AND TO IMPLEMENT AND CALIBRATE THE MICROSPECTROPHOTOMETER FOR USE IN DETERMINATION OF OXYGEN SATURATION OF HEMOGLOBIN IN MICROVESSELS, WITH EMPHASIS ON USING EPI-ILLUMINATION. AT THIS STAGE A SIMPLY OPERATED INSTRUMENT WOULD BE COMMERCIALLY AVAILABLE AT A RELATIVELY LOW COST FOR THE NONINVASIVE SIMULTANEOUS MEASUREMENT OF ERYTHROCYTE VELOCITY AND OXYHEMOGLOBIN SATURATION IN MICROVESSELS.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government