THE LONG TERM OBJECTIVE IS TO DEVELOP OUR NEW IMMUNOASSAY METHOD FOR USE IN THE DENTIST'S AND PHYSICIAN'S OFFICE.

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 1482
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1984
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
1725 Revere Beach Parkway, Everett, MA, 02149
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 MYRON J. BLOCK
 DIRECTOR
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
THE LONG TERM OBJECTIVE IS TO DEVELOP OUR NEW IMMUNOASSAY METHOD FOR USE IN THE DENTIST'S AND PHYSICIAN'S OFFICE. OUR METHOD WILL USE THE EVANESCENT WAVE ON THE SURFACE OF AN OPTICAL FIBER TO OPTICALLY SEPARATE BOUND FROM UNBOUND ANTIGEN/ANTIBODY AND TO MINIMIZE THE FLUORESCENT BACKGROUND OF THE SPECIMEN. THE FIBER IS IN RAW SPECIMEN CONTAINED IN A CAPILLARY TUBE WHICH MINIMIZES SPECIMEN HANDLING AND SENSITIVITY TO SPECIMEN VOLUME. IT ALSO CORRECTS FOR INTERSTITIAL VOLUME. IT WILL USE ONLY A FEW MICROLITERS OF UNPROCESSED SPECIMEN (E.G., RAW SALIVA OR WHOLE BLOOD). THE FLUORESCENT TAGGED REAGENTS WILL HAVE A LONG SHELF LIFE. THE INSTRUMENT MAY BE ABOUT THE SIZE OF A POCKET CALCULATOR. THE VARIETY OF ASSAYS POSSIBLE WILL INCLUDE HORMONES, DRUGS AND INFECTIOUS AGENTS. WE EXPECT THAT OUR METHOD WILL MAKE IMMUNOASSAY PRACTICAL FOR USE IN THE DENTIST'S AND DOCTOR'S OFFICE. IT WILL HAVE AN IMPACT ON THE METHOD OF DELIVERY OF HEALTH CARE SINCE THERE WILL BE NO NEED TO WAIT FOR "RESULTS FROM THE LAB" BUT RATHER THE RESULTS WILL BE AVAILABLE DURING THE VISIT. THE SPECIFIC AIM IS TO DETERMINE THE ACCURACY OF THE INTERSTITIAL VOLUME CORRECTION IN RAW SALIVA.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government