THE SENSITIVITY OF A NEW IMMUNOANALYSIS OF SMALL VOLUME RAW SPECIMENS

Award Information
Agency:
National Aeronautics and Space Administration
Branch
n/a
Amount:
$486,600.00
Award Year:
1984
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Award Id:
663
Agency Tracking Number:
663
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1725 Revere Beach Pkwy, Everett, MA, 02149
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Myron J. Block
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
THIS PROJECT INVESTIGATES THE SENSITIVITY OF A NEW METHOD OF IMMUNOANALYSIS TO DETERMINE ITS APPLICABILITY FOR USE IN A SPACECRAFT ENVIRONMENT. ITS CHARACTERISTICS ARE: USE OF UNPROCESSED SPECIMENS (E.G., WHOLE BLOOD AND SALIVA),A SAMPLE VOLUME OF 3 MICROLITERS, MULTIPLE DETERMINATIONS PER SPECIMEN, AND INSENSITIVITY TO SAMPLE VOLUME. THE SIZE OF A TEST KIT WILL BE ONLY 1/4 CC; IT WILL HAVE A MINIMUM OFMANUAL OPERATIONS; AND IT WILL NOT REQUIRE A SEPARATION OF BLOOD FROM UNBOUND ANTIGEN/ANTIBODY. THE FLUORESCENT TAGGEDREAGENTS HAVE A VERY LONG SHELF LIFE. THE INSTRUMENT FOR READING OUT THE FLUORESCENCE MAY BE ABOUT THE SIZE OF A LARGE POCKET CALCULATOR. THESE CHARACTERISTICS, WHICH ENABLE IMMUNOASSAY TO BE PERFORMED IN THE DOCTOR'S OFFICE, ARE IDEAL FOR THE SPACE CRAFT ENVIRONMENT. IN ADDITION, EVERY STEP OF THE ASSAY CAN OPERATE IN ZERO GRAVITY. THE VARIETY OF ASSAYS POSSIBLE INCLUDE HORMONES AND INFECTIOUS AGENTS.

* information listed above is at the time of submission.

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