RAPID FIBEROPTIC FLUORO-IMMUNOASSAY OF CANNABINOIDS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$488,000.00
Award Year:
1989
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Award Id:
7410
Agency Tracking Number:
7410
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Po Box 50, Nahant, MA, 01908
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Myron J Block
(617) 592-3650
Business Contact:
() -
Research Institute:
n/a
Abstract
THE PROJECT'S LONG-TERM OBJECTIVE IS TO DEVELOP A VERY SENSITIVE POCKET-SIZE FIBEROPTIC FLUORO-IMMUNOASSAY (FFIA) SYSTEM FOR THE DETECTION OF DRUGS OF ABUSE. THIS DETECTION WILL BE EITHER OF INDIVIDUAL DRUGS OR SIMULTANEOUSLY OF 1 OR MORE DRUGS IN A PANEL OF UP TO 50 DRUGS, AND WILL TAKE LESS THAN 30 SECONDS. SIMULTANEOUS DETECTION WILL BE DONE ON A SINGLE SPECIMEN WITHOUT ANY SAMPLE PREPARATION OR SAMPLE VOLUME MEASUREMENT. THERE ARE TWO SPECIFIC AIMS. THE FIRST IS TO DETERMINE THE FEASIBILITY OF ORD'S FFIA METHOD FOR THE DETECTION OF CANNABINOIDS. THE PROPOSED SENSITIVITY GOAL IS 10 NG/ML OF THE TETRAHYDRO-CANNABINOL (THC) URINARY METABOLITE. ALTHOUGH AN ASSAY IS PROPOSED FOR URINARY METABOLITES, ORD'SMETHOD HAS THE POTENTIAL FOR MEASURING THE FREE DRUG DIRECTLY IN A DROP OF WHOLE BLOOD WITHOUT ANY SEPARATION STEPS. THE SECOND SPECIFIC AIM IS TO MODIFY THE FFIA INSTRUMENT FOR AN INVESTIGATION INTO OPTIMIZING FIBER AREA TO ALLOW FOR THE MAXIMUM NUMBER OF DRUGS TO BE DETECTED SIMULTANEOUSLY.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government