ORIGINUS, INC.

Basic Information

3970 VARSITY DRIVE
ANN ARBOR, MI, -

Company Profile

n/a

Additional Details

Field Value
DUNS: 100651889
Hubzone Owned: N
Socially and Economically Disadvantaged: N
Woman Owned: N
Number of Employees: n/a


  1. NOVEL HIGH THROUGHPUT PLATFORM FOR SCREENING CYTOCHROME P450 INDUCTION

    Amount: $870,493.00

    DESCRIPTION (provided by applicant): Many prescribed drugs exhibit drug-drug interactions due to up-regulation or inhibition of specific P450 enzymes. According to a recent guidance from the FDA, CYP1 ...

    SBIR Phase II 2012 Department of Health and Human Services
  2. NOVEL HIGH THROUGHPUT PLATFORM FOR SCREENING CYTOCHROME P450 INDUCTION

    Amount: $222,421.00

    DESCRIPTION (provided by applicant): Metabolism of administered drugs is determined by expression and activity of drug-metabolizing enzymes, such as cytochrome (CYP) P450 enzymes. These P450s are subj ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. RAPID NEURAL DIFFERENTIATION OF HUMAN STEM CELLS: A NOVEL DRUG DISCOVERY PLATFORM

    Amount: $694,281.00

    DESCRIPTION (provided by applicant): A current major challenge in pharmaceutical industry is to develop treatments for brain diseases and mental disorders such as depression, anxiety, schizophrenia, e ...

    SBIR Phase I 2009 Department of Health and Human Services
  4. DEVELOPMENT OF HIGH DENSITY DRUG SCREENING OF NEURAL GPCR's USING STEP ARRAYS

    Amount: $492,783.00

    DESCRIPTION (provided by applicant): Recent advances in genomics and proteomics have produced rapid changes in drug discovery, increasing the speed of the High Throughput Screening (HTS) methods by us ...

    SBIR Phase I 2008 Department of Health and Human Services
  5. Screening Method for GPCRs Related to Appetite

    Amount: $1,343,270.00

    DESCRIPTION (provided by applicant): The development of drugs aimed at reducing obesity and controlling eating disorders represents a major target of the pharmaceutical industry and has become one of ...

    SBIR Phase II 2005 Department of Health and Human Services
  6. Screening Method for GPCRs Related to Appetite

    Amount: $99,617.00

    DESCRIPTION (provided by applicant): The long-term goal of this project is to develop tools for high throughput testing of drug compounds from combinatorial libraries that target G-Protein-Coupled Rec ...

    SBIR Phase I 2004 Department of Health and Human Services

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