Microarray chips for rapid detection of high affinity nucleic acid sequences
Small Business Information
2-212 CTR FOR SCI & TECH, 111 COLLEGE PL, SYRACUSE, NY, 13244
AbstractDESCRIPTION (provided by applicant): This phase I project aims at demonstrating a method to rapidly discover short sequences that bind tightly to protein targets. Our plan in phase I is limited to proof of principle by screening against fluorescently tagged proteins, which will facilitate analysis. In phase II label-free detection methods of analysis will be pursued in an effort to generalizes the screening method. Oligonucleotides discovered in these screens can be engineered into sensors having exquisite sensitivity and selectivity for diagnostics and drug discovery applications.
* information listed above is at the time of submission.