Microarray chips for rapid detection of high affinity nucleic acid sequences

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$112,494.00
Award Year:
2006
Program:
SBIR
Phase:
Phase I
Contract:
1R43GM076811-01A1
Agency Tracking Number:
GM076811
Solicitation Year:
2006
Solicitation Topic Code:
n/a
Solicitation Number:
PHS2006-2
Small Business Information
ORTHOSYSTEMS, INC.
2-212 CTR FOR SCI & TECH, 111 COLLEGE PL, SYRACUSE, NY, 13244
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
MARK MCPIKE
(315) 443-5356
MPMCPIKE@ORTHOBIOSYSTEMS.COM
Business Contact:
MARK MCPIKE
(315) 633-2423
mpmcpike@orthobiosystems.com
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): This phase I project aims at demonstrating a method to rapidly discover short sequences that bind tightly to protein targets. Our plan in phase I is limited to proof of principle by screening against fluorescently tagged proteins, which will facilitate analysis. In phase II label-free detection methods of analysis will be pursued in an effort to generalizes the screening method. Oligonucleotides discovered in these screens can be engineered into sensors having exquisite sensitivity and selectivity for diagnostics and drug discovery applications.

* information listed above is at the time of submission.

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