Microarray Chips for Rapid Detection of High Affinity Nucleic Acid Sequences.

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 2R44GM076811-02
Agency Tracking Number: GM076811
Amount: $973,455.00
Phase: Phase II
Program: SBIR
Awards Year: 2008
Solicitation Year: 2008
Solicitation Topic Code: N/A
Solicitation Number: PHS2007-2
Small Business Information
DUNS: 138843722
HUBZone Owned: Y
Woman Owned: Y
Socially and Economically Disadvantaged: Y
Principal Investigator
 () -
Business Contact
Phone: (315) 633-2423
Email: pborer@twcny.rr.com
Research Institution
DESCRIPTION (provided by applicant): This Phase II project aims at further advancing and commercializing a microarray-based screening approach, for discovering nucleic acid probes that have high affinity and high specificity for protein and cellular target s. Oligonucleotides discovered in these screens can be engineered into sensors having exquisite sensitivity and selectivity for drug development, environmental sensing and POC-diagnostics; areas currently dominated by antibody based technologies. In Phase II we plan to pursue protein targets that are relevant to each of these market segments, in an effort streamline the commercialization process and establish a broad product portfolio. PUBLIC HEALTH RELEVANCE: The Combigen screening process being fur ther developed in this phase II project will create molecular probes that specifically bind protein based targets. These probes will find applications in environmental sensing, point-of-care diagnostics and drug therapies.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government