OXFORD BIOMEDICAL RESEARCH, INC.

Company Information

Company Name
OXFORD BIOMEDICAL RESEARCH, INC.
Address
2165 AVON INDUSTRIAL DRIVE
ROCHESTER HILLS, MI, 48309-
Phone
1 248-852-8815
URL
n/a
DUNS
n/a
Number of Employees
n/a

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$2,079,708.00
34
SBIR Phase II
$6,025,181.00
15
STTR Phase I
$85,395.00
1
Chart code to be here

Award List

  1. DEVELOPMENT OF ALTERNATIVE, EXOGENOUS METABOLISM SYSTEMS FOR

    Amount: $374,000.00

    THE IDENTIFICATION OF MUTAGENIC COMPOUNDS IS AN IMPORTANT SOCIETAL GOAL. SHORT-TERM TESTS THAT EMPLOY MAMMALIAN ENZYMES (GENERALLY MIXED-FUNCTION OXIDASES FROM RAT LIVER) TO PROVIDE METABOLIC ACTIVATI ...

    SBIR Phase II 1986 Department of Health and Human Services
  2. PEROXIDASE ACTIVATION

    Amount: $50,000.00

    ASSAYS THAT EMPLOY MAMMALIAN ENZYMES (GENERALLY MIXED- FUNCTION OXIDASES FROM RAT LIVER) TO PROVIDE METABOLIC ACTIVATION OF PREMUTAGENS TO ULTIMATE MUTAGENS HAVE BEEN DEVELOPED AND ARE WIDELY USED TO ...

    SBIR Phase I 1986 Department of Health and Human Services
  3. ISOLATION AND PURIFICATION OF PROSTACYCLIN SYNTHASE

    Amount: $487,390.00

    PROSTACYCLIN SYNTHASE (PGI2 SYNTHASE) CATALYZES AN INTRAMOLECULAR REDOX REACTION IN WHICH PROSTAGLANDIN ENDOPEROXIDE, PGH2, IS CONVERTED TO PROSTACYCLIN, PGI2. THE POTENT BIOLOGICAL ACTIVITIES OF PGI2 ...

    SBIR Phase II 1991 Department of Health and Human Services
  4. DEVELOPMENT OF PROBES FOR INVESTIGATION OF ORGANIC ACIDURIAS

    Amount: $47,395.00

    GLUTARYL-COA DEHYDROGENASE (GCDH), AN ENZYME COMMON TO LYSINE, HYDROXYLYSINE, AND TRYPTOPHAN CATABOLISM, CATALYZES THE CONVERSION OF GLUTARYL-COA TO CROTONYL-COA. LACK OF GCDH ACTIVITY IN HUMANS IS CH ...

    SBIR Phase I 1990 Department of Health and Human Services
  5. HUMAN LIPOXYGENASE PRUFICATION AND MOLECULAR PROBES

    Amount: $49,996.00

    LIPOXGENASES CONSTITUTE A FAMLY OF NON-HEME IRON-CONTAINING DIOXYGENASES THAT HAVE BEEN DEMONSTRATED TO PRODUCE A WIDE RANGE PHYSIOLOGICALLY ACTIVE METABOITES. THE ENZYME 12-LIPOXYGENASE (12-LX) IS PR ...

    SBIR Phase I 1992 Department of Health and Human Services
  6. Prostaglandin Synthase-2--Purification and Immunoassay

    Amount: $377,998.00

    This project will develop methods for large scale production and quantification of humanprostaglandin H synthase-2 (PGHS-2), a recently discovered enzyme that is differentially regulated andhas signif ...

    SBIR Phase II 1996 Department of Health and Human Services
  7. Develop Assay for 9,11 3-Hydroxyoctadecadienoic Acid

    Amount: $75,000.00

    Linoleic acid, the predominant polyunsaturated fatty acid (PUFA) in the human diet, can bemetabolized by cyclooxgenase, lipoxygenase and P450 enzymes. The monohydroxy derivatives oflinoleic acid, 9(S) ...

    SBIR Phase I 1994 Department of Health and Human Services
  8. Molecular Probes for an Oncogene Regulatory Protein

    Amount: $80,208.00

    The development of cancer is a complex process that appears to involve multiple mechanisms.Recent studies indicate that the Her-2/neu (ERBB2) gene may be important in the transformation ofnormal breas ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. Immunoassay for A Non-Enzymatic Arachidonate Derivative

    Amount: $463,462.00

    A novel class of postaglandin F2-like compounds formed in vitro or in vivo by a free-radical catalyzed noncyclocxygenase mechanism have recently been discovered. For normal humans. Levels of these com ...

    SBIR Phase II 1994 Department of Health and Human Services
  10. Development of Antibodies for Drug Metabolizing Enzymes

    Amount: $419,964.00

    We will develop and market a comprehensive collection of antibodies specific for enzymes that play a significant role in drug metabolism . Availability of specific antibodies will greatly facilitate s ...

    SBIR Phase II 1994 Department of Health and Human Services

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