CROSS-AXIS COIL PLANET CENTRIFUGE CHROMATOGRAPH

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1988
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
8047
Agency Tracking Number:
8047
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Box 368 Main, 125 Michigan Ave Ne, Washington, DC, 20017
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
() -
Business Contact:
() -
Research Institute:
n/a
Abstract
A NEW COUNTERCURRENT CHROMATOGRAPHY INSTRUMENT, THE CROSS-AXIS, FLOW-THROUGH COIL PLANET CETRIFUGE, WHICH IS EQUIPPED WITH ECCENTRICALLY ORIENTED MULTILAYER COILS, IS PROPOSED FOR THE PREPARATIVE CHROMATOGRAPHY OF PEPTIDES. THIS IS AN APPARATUS THAT SEPARATES SUBSTANCES ACCORDING TO THEIR PARTITIONING IN A LIQUID-LIQUID EQUILIBRATION SYSTEM WITHOUT THE USE OF A SOLID-PHASE SUPPORT. THE INSTRUMENT WILL BE TESTED IN THE PURIFICATION OF LARGE QUANTITIES OF SYNTHETIC PEPTIDES, USING DIFFERENT CONDITIONS AND SOLVENT SYSTEMS TO ACHIEVE HIGH RESOLUTION AND RECOVERY. THE SUCCESSFUL DEVELOPMENT OF THIS INSTRUMENT WOULD MAKE AVAILABLE A LOWER COST TECHNOLOGY FOR CHROMATOGRAPHIC PURIFICATION.

* information listed above is at the time of submission.

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