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DIAGNOSIS OF NATURAL AND INDUCED DISEASES OF MILITARY IMPORTANCE

Award Information
Agency: Department of Defense
Branch: Army
Contract: N/A
Agency Tracking Number: 12813
Amount: $50,219.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 1990
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
2545 W 237th St - Ste B
Torrance, CA 90505
United States
DUNS: N/A
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Dr Gajendra Savant
 (213) 320-3088
Business Contact
Phone: () -
Research Institution
N/A
Abstract

PHYSICAL OPTICS CORPORATION (POC) IS PROPOSING A COMPLETELY NEW HIV TEST WHICH IS BASED ON A HIGHLY SENSITIVE LIGAND RECEPTOR BINDING STUDY DEVELOPED AT POC. IN THIS PROGRAM, THE FEASIBILITY OF DESIGNING A POLARIZATION FLUORIMETER DEVICE FOR AIDS VIRUS DETECTION WILL BE INVESTIGATED, AS WILL A METHOD OF MEASURMENT USING THE DEVICE. SUCH A DEVICE SHOULD BE CAPABLE OF IDENTIFYING THE AGENT WITH A HIGH ACCURACY AND WITH REPRODUCIBLE RESULTS. IT SHOULD ALSO BE INEXPENSIVE, SIMPLE AND PORTABLE FOR USE IN PHYSICIANS OFFICES, SMALL DIAGNOSTIC LABORATORIES AND HOSPITALS. MATTERS TO BE INTENSIVELY STUDIED WITHIN THE TIME FRAME OF PHASE I INCLUDE DEVICE DESIGN, OPTO-ELECTRONIC ELEMENT REQUIREMENTS, REPRODUCIBILITY AND THE ACCURACY OF THE MEASURMENTS. FLUORESCENT ANALYSIS OF A PEPIDANTIBODY REACTION IS VERY SENSITIVE AND FAST AND THE POLARIZATION METHOD PROVIDES A QUALITATIVE RESULT. BASED ON POC'S HOLOGRAPHIC FILTERS, POLARIZERS AND PLANAR WAVE GUIDES FABRICATED IN POC'S LABORATORY, VERY COMPACT CONSTRUCTION OF SUCH A DEVICE IS POSSIBLE. ALSO, DUE TO THE LOW COST OF HOLOGRAPHIC OPTICAL ELEMENTS AND LIGHT SOURCES, THE GOAL OF COST EFFECTIVENESS WILL BE ACHIEVED. THE NUMERICAL RESULTS YIELDED BY THIS TEST WILL MAKE THE DEVICE AND METHOD SIMPLE TO USE, EVEN FOR INEXPERIENCED PERSONNEL.

* Information listed above is at the time of submission. *

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