Nanostructured substrates for cell assays

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 2R44GM069026-03
Agency Tracking Number: GM069026
Amount: $1,578,880.00
Phase: Phase II
Program: SBIR
Awards Year: 2005
Solicitation Year: 2005
Solicitation Topic Code: N/A
Solicitation Number: PHS2005-2
Small Business Information
Platypus Technologies, Llc, 5520 Nobel Drive, Suite 100, Madison, WI, 53711
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 (608) 441-2776
Business Contact
Phone: (608) 237-1272
Research Institution
DESCRIPTION (provided by applicant): Our goal in this Phase 2 SBIR proposal is to develop and optimize the components for a novel cell migration assay. In Phase 1, we demonstrated that liquid crystals assume a predictable orientation in response to cellular membranes, and therefore they could be used in a sensitive, rapid, generalizable method for reporting cell number. In this application, we propose to build on the ability of liquid crystals to accurately report cell number and spatial location in the development of a quantitative assay for cell migration. This innovative approach will provide a technology with many intrinsic advantages over current methods by reducing labor, time and cost and by providing compatibility with high throughput formats.

* Information listed above is at the time of submission. *

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