Nanostructured substrates for cell assays

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$1,578,880.00
Award Year:
2005
Program:
SBIR
Phase:
Phase II
Contract:
2R44GM069026-03
Agency Tracking Number:
GM069026
Solicitation Year:
2005
Solicitation Topic Code:
n/a
Solicitation Number:
PHS2005-2
Small Business Information
PLATYPUS TECHNOLOGIES, LLC
Platypus Technologies, Llc, 5520 Nobel Drive, Suite 100, Madison, WI, 53711
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
BARBARA ISRAEL
(608) 441-2776
bisrael@platypustech.com
Business Contact:
SUSAN PSCHORR
(608) 237-1272
SPSCHORR@PLATYPUSTECH.COM
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): Our goal in this Phase 2 SBIR proposal is to develop and optimize the components for a novel cell migration assay. In Phase 1, we demonstrated that liquid crystals assume a predictable orientation in response to cellular membranes, and therefore they could be used in a sensitive, rapid, generalizable method for reporting cell number. In this application, we propose to build on the ability of liquid crystals to accurately report cell number and spatial location in the development of a quantitative assay for cell migration. This innovative approach will provide a technology with many intrinsic advantages over current methods by reducing labor, time and cost and by providing compatibility with high throughput formats.

* information listed above is at the time of submission.

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