Development of Non-Invasive Deep Tissue pH Sensor

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$583,856.00
Award Year:
1996
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Award Id:
28777
Agency Tracking Number:
28777
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
79 Maynard Road, Sudbury, MA, 01776
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Mary Beth Tabacco,
(508) 443-8125
Business Contact:
() -
Research Institute:
n/a
Abstract
Tissue pH is a good indicator of the poor blood flow/poor oxygenation condition called ischemia, and can be used to assess tissue viability. Polestar Technologies, Inc. proposes a program to develop a non-invasive tissue pH sensor and monitoring system which utilizes the intrinsic light absorbing or emitting properties of pigments present in muscle and organ tissue. This Phase I effort proposes to evaluate two different optical methods for measuring tissue pH by collecting data from an animal model of ischemia. Optical signals from exposed muscle, as well as deep muscle tissue obscured by skin will be evaluated. Data collected by the non-invasive optical sensor will be correlated with pH measured by tissue pH electrodes to determine the most sensitive method for optically measuring pH and the appropriate wavelengths for use in the final sensor design. The goal of this project is to develop a conceptual design for a lightweight, portable, optical-based sensor and monitor capable of measuring pH for the assessment of tissue viability.

* information listed above is at the time of submission.

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