High Resolution, Low Cost Small Animal PET Imager

Award Information
Agency:
Department of Energy
Branch
n/a
Amount:
$99,990.00
Award Year:
2001
Program:
SBIR
Phase:
Phase I
Contract:
DE-FG02-01ER83256
Award Id:
51824
Agency Tracking Number:
65685S01-I
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
220 Reservoir Street, Suite 32, Needham Heights, MA, 02494
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
JamesKane
Vice President, Operations
(781) 449-2284
polestar@ix.netcom.com
Business Contact:
KarenCarpenter
President
(781) 449-2284
polestar@ix.netcom.com
Research Institute:
n/a
Abstract
65685 A deeper understanding of microbial processes and their physiological status in various soils and pore structures is needed in order to optimize bioremediation process. However, it is difficult to determine the influence of physical and/or geochemical forces on the efficiency of bioremediation processes at the pore-scale (i.e. 10 micron and smaller) because of a lack of high-spatial-resolution instrumentation. This project will develop new optical technology for the detection of bioactivity at the pore-scale by the use of CO2 sensing nanospheres. The system will be demonstrated first in laboratory experiments using soil columns and then in conjunction with a field deployable probe such as a cone penetrometer. Phase I will include the synthesis of a unique CO2 indicator and the characterization of this compound in polymeric films and nanospheres. Data will be collected to determine sensitivity, stability, and selectivity using phase-sensitive fluorescence lifetime detection. Commercial Applications and Other Benefits as described by awardee: In addition to its use in bioremediation research, the proposed CO2-sensing technology should address a need for an improved CO2 sensor in several biotechnological and industrial applications involving fermentation, cell culture, as well as food and beverages.

* information listed above is at the time of submission.

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