Novel Antibacterial Agents

Award Information
Agency:
Department of Defense
Branch
Navy
Amount:
$69,891.00
Award Year:
2009
Program:
STTR
Phase:
Phase I
Contract:
N00014-09-M-0357
Award Id:
90350
Agency Tracking Number:
N09A-033-0128
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
170 N. Radnor-Chester Road, Suite 300, Radnor, PA, 19087
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
621470033
Principal Investigator:
Richard Scott
VP Research, PolyMedix
(484) 598-2336
rscott@polymedix.com
Business Contact:
Dawn Eringis
Director Scientific Affairs, PolyMe
(484) 598-2334
deringis@polymedix.com
Research Institution:
University of Massachusetts, Amhers
Carol P Sprague
Research Administration Bldg
70 Butterfield Terrace
Amherst, MA, 1003
(413) 545-0698
Nonprofit college or university
Abstract
The need for novel antibiotics is well understood by anyone familiar to the field. We have discovered a novel class of antibiotics that are structurally unique from all previously known antibiotics and appear to operate via a distinctive mode of action. As a result, these new agents appear to represent significant promise as new treatments for the emerging problem of MDR infections. In less than 5 years, PolyMedix has translated one of these novel molecules from discovery to Phase 1a human clinical trials with a planned indication to broadly treat Staphylococcal infections including methicillin-resistant S. aureus. This proposal describes our efforts to develop lead compounds against those pathogens most relevant to military personnel with a specific focus on Acinetobacter and P. aeruginosa.

* information listed above is at the time of submission.

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