THE MAJOR GOAL OF THIS PROJECT IS TO PREPARE SMALL, MONODISPERSED RESIN LATICES THAT MAY BE MAGNETIZED BY AN EXTERNAL MAGNETIC FIELD.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1986
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
4772
Agency Tracking Number:
4772
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
400 Valley Road, Warrington, PA, 18976
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
WOLF KARO
PRINCIPAL INVESTIGATOR
(215) 343-6484
Business Contact:
() -
Research Institution:
n/a
Abstract
THE MAJOR GOAL OF THIS PROJECT IS TO PREPARE SMALL, MONODISPERSED RESIN LATICES THAT MAY BE MAGNETIZED BY AN EXTERNAL MAGNETIC FIELD. THE IMMEDIATE APPLICATION OF SUCH MATERIAL-AFTER COUPLING TO SUITABLE ANTIBODIES-IS AS NMR IMAGE CONTRASTING AGENTS FOR THE EARLY DETECTION OF CANCER OR CANCER METASTASES THAT ARE TOO SMALL FOR DETECTION BY PRESENT METHODS. TH ACHIEVE THIS GOAL, DISPERSIONS OF MAGNETIZABLE INORGANIC OXIDES IN STYRENE ARE TO BE POLYMERIZED IN THE PRESENCE OF VARYING LEVELS OF SURFACTANTSTO CONTROL PARTICLE SIZE AND, IN THE PRESENCE OF ONE OF SEVERAL FUNCTIONAL MONOMERS, TO ENHANCE CAPABILITY TO BOND COVALENTLY TO PROTEINS. THE EFFECT OF COATING MAGNETIZABLE WITH SHELLS OF INERT POLYMERS WILL BE EVALUATED. THE SPECIFIC AIM OF THIS PHASE I RESEARCH IS TO PROVIDE MATERIALS AS INDICATED.

* information listed above is at the time of submission.

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