THE SWEPT FIELD CONFOCAL MICROSCOPE

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$142,251.00
Award Year:
2002
Program:
SBIR
Phase:
Phase I
Contract:
1R43MH065724-01
Award Id:
61092
Agency Tracking Number:
MH065724
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
PRAIRIE TECHNOLOGIES, INC., 3230 DEMING WAY, STE 175, MIDDLETON, WI, 53562
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
MICHAEL SZULCZEWSKI
(608) 662-0022
MIKES@PRAIRIE-TECHNOLOGIES.COM
Business Contact:
MICHAEL SZULCZEWSKI
(608) 662-0022
MIKES@PRAIRIE-TECHNOLOGIES.COM
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant) Confocal microscopy is an essential tool for the biological sciences. It has significantly enhanced the testing of hypotheses in the Neurosciences and has provided insights into the causes of neurological disorders. The goal of this project is to develop a new type of confocal microscope based on a new concept, the swept-field confocal design (SFC). The SFC has the potential of becoming an attachment for the light microscope that could be purchased by the individual scientist for under $50,000. The SFC is a revolutionary confocal concept in which this hybrid-instrument uses an 86 x 12 array of stationary pinholes for illumination and detection along one axis (e.g. the Y axis) while using one galvanometer to sweep the illumination along the X axis. This phase I project has five specific objectives. We will: 1) Design and build a swept-field confocal microscope; 2) modify existing digital camera acquisition software to make SFC control software; 3) Compare the optical efficiency and resolution of the SFC and present day LSCMs; 4) Calculate the manufacturing costs of the SFC and determine whether the SFC could come to market at $45,000, and finally 5) Test the performance of the swept-field confocal microscope in biological applications.

* information listed above is at the time of submission.

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