Low Cost 62ZN/62CU Generator for Multi Organ PET Imaging

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1 R43 RR09880-1,
Agency Tracking Number: 25277
Amount: $739,072.00
Phase: Phase II
Program: SBIR
Awards Year: 1995
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
8018 El Rio, Houston, TX, 77054
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Jeffrey Lacy
 (713) 747-7324
Business Contact
Phone: () -
Research Institution
N/A
Abstract
Positron emission tomography (PET) is recognized as a superior diagnostic imaging techniquein a number of important clinical areas. However, it is currently relegated to a research role due to itsdependence upon in-hospital cyclotrons for radioisotope production with resultant high cost andpotentially unresolvable regulatory issues. We will develop a commercially practical and economical62Zn/62Cu generator for PET radiopharmaceutical production. The versatile chemistry and short 9.7minute half-life of 62Cu make it a very promising agent for a wide variety of PET procedures. However,the 9.3 hour half-life of the 62Zn parent isotope poses substantial commercial challenges since itrequires daily preparation and delivery of the generator. Because PTI has developed and is routinelyproducing the 178W/178Ta generator system with similar technical issues, it is uniquely equipped toundertake this development. The availability of a 62Zn/62Cu generator compatible with straightforwardFDA approval and low cost commercial distribution could elevate the PET technique to the importantclinical role it deserves.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government