Low Cost 62ZN/62CU Generator for Multi Organ PET Imaging

Award Information
Agency:
Department of Health and Human Services
Branch:
N/A
Amount:
$739,072.00
Award Year:
1995
Program:
SBIR
Phase:
Phase II
Contract:
1 R43 RR09880-1,
Agency Tracking Number:
25277
Solicitation Year:
N/A
Solicitation Topic Code:
N/A
Solicitation Number:
N/A
Small Business Information
Proportional Technologies,
8018 El Rio, Houston, TX, 77054
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
N/A
Principal Investigator
 Jeffrey Lacy
 (713) 747-7324
Business Contact
Phone: () -
Research Institution
N/A
Abstract
Positron emission tomography (PET) is recognized as a superior diagnostic imaging techniquein a number of important clinical areas. However, it is currently relegated to a research role due to itsdependence upon in-hospital cyclotrons for radioisotope production with resultant high cost andpotentially unresolvable regulatory issues. We will develop a commercially practical and economical62Zn/62Cu generator for PET radiopharmaceutical production. The versatile chemistry and short 9.7minute half-life of 62Cu make it a very promising agent for a wide variety of PET procedures. However,the 9.3 hour half-life of the 62Zn parent isotope poses substantial commercial challenges since itrequires daily preparation and delivery of the generator. Because PTI has developed and is routinelyproducing the 178W/178Ta generator system with similar technical issues, it is uniquely equipped toundertake this development. The availability of a 62Zn/62Cu generator compatible with straightforwardFDA approval and low cost commercial distribution could elevate the PET technique to the importantclinical role it deserves.

* information listed above is at the time of submission.

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