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Low Cost 62ZN/62CU Generator for Multi Organ PET Imaging

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1 R43 RR09880-1,
Agency Tracking Number: 25277
Amount: $739,072.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 1995
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
8018 El Rio
Houston, TX 77054
United States
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Jeffrey Lacy
 (713) 747-7324
Business Contact
Phone: () -
Research Institution

Positron emission tomography (PET) is recognized as a superior diagnostic imaging techniquein a number of important clinical areas. However, it is currently relegated to a research role due to itsdependence upon in-hospital cyclotrons for radioisotope production with resultant high cost andpotentially unresolvable regulatory issues. We will develop a commercially practical and economical62Zn/62Cu generator for PET radiopharmaceutical production. The versatile chemistry and short 9.7minute half-life of 62Cu make it a very promising agent for a wide variety of PET procedures. However,the 9.3 hour half-life of the 62Zn parent isotope poses substantial commercial challenges since itrequires daily preparation and delivery of the generator. Because PTI has developed and is routinelyproducing the 178W/178Ta generator system with similar technical issues, it is uniquely equipped toundertake this development. The availability of a 62Zn/62Cu generator compatible with straightforwardFDA approval and low cost commercial distribution could elevate the PET technique to the importantclinical role it deserves.

* Information listed above is at the time of submission. *

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