THE PLASMA PROTEINS REPRESENT THE MOST THOROUGHLY CATALOGUEDGROUP OF HUMAN PROTEINS.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1986
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
4952
Agency Tracking Number:
4952
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
12301 Parklawn Drive, Rockville, MD, 20852
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
NORMAN LEIGH ANDERSON
PRINCIPAL INVESTIGATOR
(301) 881-2600
Business Contact:
() -
Research Institute:
n/a
Abstract
THE PLASMA PROTEINS REPRESENT THE MOST THOROUGHLY CATALOGUEDGROUP OF HUMAN PROTEINS. HIGH-RESOLUTION, TWO-DIMENSIONAL ELECTROPHORESIS HAS ALLOWED THE CONSTRUCTION OF COMPREHEN- SIVE MAPS OF THE PLASMA PROTEINS AND MAKES POSSIBLE THE CONSTRUCTION OF A PROTEIN INDEX DATABASE COVERING THEIR MOLECULAR AND OTHER PROPERTIES. RESEARCHERS HAVE IDENTIFIED40 POLYPEPTIDE COMPONENTS ON THE PLASMA PROTEIN MAP, LEAVINGPERHAPS 100 PROTEINS DETECTED BUT UNIDENTIFIED. THIS PROJECT CONCERNS AN EFFORT TO IDENTIFY AS MANY OF THE REMAINING KNOWN PROTEINS AS POSSIBLE AND TO BEGIN COLLECTIONOF PERTINENT MOLECULAR DATA FOR EACH PROTEIN IN ORDER TO CREATE A USEFUL HUMAN PLASMA PROTEIN INDEX. BOTH EXPERIMENTALLY-DERIVED AND LITERATURE-DERIVED DATA WILL BE INCLUDED. IN PHASE II, THIS DATABASE WILL BE MADE AVAILABLEON LINE TO RESEARCHERS CONCERNED WITH PLASMA PROTEIN ANALYSIS.

* information listed above is at the time of submission.

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