MicroFlex Tools to Improve Sinus Diagnostics and Surgery

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$997,195.00
Award Year:
2008
Program:
STTR
Phase:
Phase II
Contract:
2R42AI063892-02A2
Agency Tracking Number:
AI063892
Solicitation Year:
2008
Solicitation Topic Code:
n/a
Solicitation Number:
PHS2007-2
Small Business Information
QUEST PRODUCT DEVELOPMENT CORPORATION
4900 Iris Street, WHEAT RIDGE, CO, 80033
Hubzone Owned:
Y
Socially and Economically Disadvantaged:
Y
Woman Owned:
Y
Duns:
958218406
Principal Investigator:
() -
Business Contact:
(303) 670-5088
alank@quest-corp.com
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): MicroFlex technology will provide unprecedented flexibility and controllability for the tip of endoscopes, enabling minimally invasive surgery in previously inaccessible spaces, direct visualization of structures there, and fine tool manipulation capabilities for diagnostic, therapeutic and surgical procedures. MicroFlex combines innovations in actuation, sensing, control and assembly to produce a 3mm diameter digitally or robotically controlled endoscope more flexible a nd controllable than those currently available. This project will use technology proven in the Phase I study to fabricate and functionally test MicroFlex prototypes for sinus diagnosis and surgery. MicroFlex prototypes will be assembled and tested in the laboratory for force and motion capabilities, a control manipulative and associated control electronics and software will be developed, and rhinologists will test the integrated system in cadavers for function and usability. Since the MicroFlex tip is controlled by temperature change in internal actuator elements, thermal effects on surrounding tissue will be assessed in detail, including advanced engineering models for temperature distribution and live animal testing for thermal damage. Sterilizatio n robustness and effectiveness of a prototype device will also be tested. MicroFlex technology, fabrication processes and prototypes will be refined by integrating input from practicing sinus surgeons, engineers with expertise in medical product de sign, and prospective Phase III manufacturing partners and suppliers of complementary navigation and visualization technology. Potential Phase III manufacturing partners will be identified and utilized for Phase II prototype components, where possible, to accelerate the commercialization process. MicroFlex Tools to Improve Sinus Diagnostics and Surgery

* information listed above is at the time of submission.

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