DEVELOPMENT OF A PC-BASED SYSTEM FOR ELECTRON MICROSCOPES

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 7376
Amount: $500,000.00
Phase: Phase II
Program: SBIR
Awards Year: 1989
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Rj Lee Group
350 Hochberg Rd, Monroeville, PA, 15146
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Richard J Lee Phd
 (412) 325-1776
Business Contact
Phone: () -
Research Institution
N/A
Abstract
IT IS PROPOSED THAT A PERSONAL COMPUTER (PC)-BASED SYSTEM BE DEVELOPED THAT WILL PROVIDE A COST-EFFECTIVE METHOD FOR COLLECTING, PROCESSING, AND ANALYZING IMAGE DATA IN ELECTRONMICROSCOPES. WIDESPREAD USE OF THIS TECHNOLOGY FOR HEALTH AND BIOMEDICAL RESEARCH WOULD BE FEASIBLE IF LESS EXPENSIVE INSTRUMENTATION WERE AVAILABLE. A PC-BASED SYSTEM IS NEEDED BECAUSE THE PRACTICAL UTILITY OF CURRENTLY AVAILABLE ELECTRON-MICROSCOPE-IMAGE ANALYSIS SYSTEMS IS LIMITED DUE TO THE COST AND COMPLEXITY OF AVAILABLE INSTRUMENTATION. THIS INSTRUMENTATION IS OF VALUEBECAUSE IMAGE ANALYSIS AND PROCESSING TECHNIQUES CAN RESOLVE SUBTLE COMPOSITION DIFFERENCES THAT ARE NOT READILY APPARENT IN THE ELECTRON MICROSCOPE IMAGE OR MICROGRAPH. THUS, SUBTLE DIFFERENCES DUE TO THE EFFECTS OF EXTERNAL AGENTS CAN BE QUALIFIED AND QUANTIFIED. THE KEY TECHNICAL INNOVATION AND GOAL OF THIS PROJECT WILL BE TO DESIGN AN INTERFACE PERMITTING THE USE OF CURRENTLY AVAILABLE, GENERAL-PURPOSE PERSONAL COMPUTERS. EFFORTS DERIVED IN THE PHASE I PROGRAM WILL EXPLORE THE FEASIBILITY OF DEVELOPING A PROTOTYPE PC-BASED SYSTEM. CONTINUED DEVELOPMENT OF THIS SYSTEM IN PHASE II AND BEYOND WILL RESULT IN A LOW-COST SYSTEM FOR COLLECTING, PROCESSING, AND ANALYZING IMAGES THAT SUCCESSFULLY INTEGRATES PC TECHNOLOGY WITH ELECTRON MICROSCOPY.

* information listed above is at the time of submission.

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government