MICROENCAPSULATED ANTIBIOTICS AND VITAMINS FOR LARVAL SHRIMP

Award Information
Agency:
Department of Agriculture
Amount:
$36,720.00
Program:
SBIR
Contract:
N/A
Solitcitation Year:
N/A
Solicitation Number:
N/A
Branch:
N/A
Award Year:
1991
Phase:
Phase I
Agency Tracking Number:
14776
Solicitation Topic Code:
N/A
Small Business Information
Rangen Aquaculture Resch Cente
Rt 1 Box 264, Hagerman, ID, 83332
Hubzone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Duns:
N/A
Principal Investigator
 Blake F Grant
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
TREATMENT OF DISEASED FINFISH AND SHRIMP LARVAE IS LIMITED TO CONTACT EXPOSURE WITH CHEMICALS ADMINISTERED IN THE WATER. HOWEVER, LARVAE REQUIRE INGESTION OF APPROPRIATE ANTIBIOTICS FOR FAST, EFFECTIVE RECOVERY FROM SYSTEMIC BACTERIAL INFECTIONS. THE AQUACULTURE INDUSTRY LACKS A MEDICATED PRODUCT DEVELOPED FOR LARVAL ANIMALS. MICROENCAPSULATION IS CURRENTLY BEING TESTED AS A DELIVERY SYSTEM OF LIVE FOOD REPLACEMENTS FOR AQUATIC LARVAL SPECIES. WE PROPOSE TO ENCAPSULATE ANTIBIOTICS AND VITAMIN SUPPLEMENTS WITHIN MICROCAPSULES SUBSEQUENTLY INCORPORATED INTO LIPID-ENRICHED MICROPARTICLES. MICROCAPSULES WILL BE PRODUCED BY A PROCESS THAT WILL PROTECT THE LOW MOLECULAR WEIGHT, WATER-SOLUBLE ANTIBIOTICS AND VITAMINS UNTIL INGESTION BY PENAEID SHRIMP LARVAE. IN-VITRO ANTIBIOTIC LEACHING RATES WILL BE CORRELATED WITH SURVIVAL OF "MEDICATED" LARVAE AGAINST VIBRIO SP. CHALLENGE TO DETERMINEFEASIBILITY FOR PHASE-II R&D. RESULTS OF IN-VITRO TESTS ANDWHOLE ANIMAL RESPONSES TO TEST MEDICATIONS, INCLUDING A CHALLENGE WITH LIVE BACTERIA, WILL DETERMINE COMMERCIALIZATION POTENTIAL.

* information listed above is at the time of submission.

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