An Automated Hollow Fiber System for the Deglycerolization of Thawed Frozen Human Blood

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$748,655.00
Award Year:
1995
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Award Id:
26624
Agency Tracking Number:
26624
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
253 Humboldt Court, Sunnyvale, CA, 94089
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Thomas C. Robinson, Phd
(408) 734-1622
Business Contact:
() -
Research Institute:
n/a
Abstract
The objectives of this proposed Phase I program are to demonstrate the feasibility and potential advantages of a new technical approach for the deglycerolizatio of thawed frozen human blood. This approach uses a hollow fiber separator to remove glycerol and saline wash solution from red cells in an efficient recirculation process that uses serial dilution. THe anticipated advantages from this apporach are: fully automatic operation; reduced processing time; reduced disposable costs; and reduced hardware size and costs compared to centrifugal machines. The proposed program will analytically model system operation, design and construct hollow fiber separators and a complete disposable blood and saline handling system, design and construct a manually operated control system simulating a microprocessor controlled system using roller pumps and tubing pinch valves, and testing this complete mockup system with blood to determine and demonstrate feasibility and potential advantages of this approach.

* information listed above is at the time of submission.

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