An Automated Hollow Fiber System for the Deglycerolization of Thawed Frozen Human Blood

Award Information
Agency: Department of Defense
Branch: Army
Contract: N/A
Agency Tracking Number: 26624
Amount: $748,655.00
Phase: Phase II
Program: SBIR
Awards Year: 1995
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
253 Humboldt Court, Sunnyvale, CA, 94089
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Thomas C. Robinson, Phd
 (408) 734-1622
Business Contact
Phone: () -
Research Institution
The objectives of this proposed Phase I program are to demonstrate the feasibility and potential advantages of a new technical approach for the deglycerolizatio of thawed frozen human blood. This approach uses a hollow fiber separator to remove glycerol and saline wash solution from red cells in an efficient recirculation process that uses serial dilution. THe anticipated advantages from this apporach are: fully automatic operation; reduced processing time; reduced disposable costs; and reduced hardware size and costs compared to centrifugal machines. The proposed program will analytically model system operation, design and construct hollow fiber separators and a complete disposable blood and saline handling system, design and construct a manually operated control system simulating a microprocessor controlled system using roller pumps and tubing pinch valves, and testing this complete mockup system with blood to determine and demonstrate feasibility and potential advantages of this approach.

* Information listed above is at the time of submission. *

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