An Automated Hollow Fiber System for the Deglycerolization of Thawed Frozen Human Blood
Small Business Information
253 Humboldt Court, Sunnyvale, CA, 94089
Thomas C. Robinson, Phd
AbstractThe objectives of this proposed Phase I program are to demonstrate the feasibility and potential advantages of a new technical approach for the deglycerolizatio of thawed frozen human blood. This approach uses a hollow fiber separator to remove glycerol and saline wash solution from red cells in an efficient recirculation process that uses serial dilution. THe anticipated advantages from this apporach are: fully automatic operation; reduced processing time; reduced disposable costs; and reduced hardware size and costs compared to centrifugal machines. The proposed program will analytically model system operation, design and construct hollow fiber separators and a complete disposable blood and saline handling system, design and construct a manually operated control system simulating a microprocessor controlled system using roller pumps and tubing pinch valves, and testing this complete mockup system with blood to determine and demonstrate feasibility and potential advantages of this approach.
* information listed above is at the time of submission.