Dry System for Thawing Frozen Blood

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$119,347.00
Award Year:
2001
Program:
SBIR
Phase:
Phase I
Contract:
DAMD17-01-C-0004
Award Id:
52922
Agency Tracking Number:
A002-2699
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
5670 Stewart Avenue, Fremont, CA, 94538
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
069123479
Principal Investigator:
ThomasRobinson
Vice President
(510) 623-3777
trobinson@missionmed.com
Business Contact:
ThomasRobinson
Vice President
(510) 623-3777
trobinson@missionmed.com
Research Institute:
n/a
Abstract
The long-term objectives of this research are to substantially improve the military frozen blood system with a number of specific devices and advances. A Dry Heat system is developed to permit very rapid thawing (under 10 minutes) instead of the 40 to 60minutes now necessary using an inconvenient, large water bath. This heating system is also used to warm IV fluids in surgery. Rapid thawing is crucial to meeting the military needs for thawed deglycerolized blood in emergencies. A new blood bag with itsprotective shipping container is developed that will have less than 3% breakage, compared to current 20% to 50% breakage in military use. The current deglycerolization process is modified to decrease the duration of the process (to under 20 minutes) and toreduce processing fluid quantities.The proposed research will evaluate the feasibility of these various approaches by fabricating and testing hardware and disposables and modifying current red cell washing processes. Military frozen blood users and bloodexperts will aid in this evaluation.These improvements to the military frozen blood system will decrease substantially (at least a factor of 2) the time needed to make red cells available in emergencies. It also reduces blood wastage, increases ease ofuse, increases user productivity, decreases costs, and improves logistics, making frozen blood far more practical for military and commercial uses.

* information listed above is at the time of submission.

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