Research Biochemicals,

Company Information

Company Name
Research Biochemicals,
Address
1 STRATHMORE RD
Natick, MA, 01760
Phone
n/a
URL
n/a
DUNS
n/a
Number of Employees
n/a
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$1,405,041.00
21
SBIR Phase II
$3,265,061.00
8

Award List

  1. HIGH AFFINITY LIGANDS FOR SPECIFIC DOPAMINE RECEPTORS

    Amount: $264,000.00

    THE DEVELOPMENT OF SAFER AND MORE EFFECTIVE ANTIPSYCHOTIC DRUGS REQUIRES THE AVAILABILITY OF SENSITIVE PROBES OF THE DOPAMINE (DA) RECEPTOR, WHICH IS A SITE OF ACTION OF THESE AGENTS. RESEARCH BIOCHEM ...

    SBIR Phase II 1987 Department of Health and Human Services
  2. THE NATURE OF THE ADENOSINE RECEPTOR WILL BE STUDIED USING ADENOSINE AGONISTS AND ANTAGONISTS MODIFIED FOR SELECTIVITY AND POSSIBLE AFFINITY LABELING.

    Amount: $50,000.00

    THE NATURE OF THE ADENOSINE RECEPTOR WILL BE STUDIED USING ADENOSINE AGONISTS AND ANTAGONISTS MODIFIED FOR SELECTIVITY AND POSSIBLE AFFINITY LABELING. ADENOSINE PLAYS A KEY ROLE IN PHYSIOLOGICAL PROCE ...

    SBIR Phase I 1986 Department of Health and Human Services
  3. HIGH AFFINITY LIGANDS FOR THE COCAINE RECEPTOR

    Amount: $404,247.00

    A SELECTIVE BINDING SITE FOR COCAINE HAS BEEN IDENTIFIED IN BRAIN MEMBRANE PREPARATIONS FROM RODENTS, MONKEYS AND HUMANS. THERE IS A HIGH DEGREE OF CORRESPONDENCE BETWEEN THE RELATIVE POTENCIES OF VAR ...

    SBIR Phase II 1990 Department of Health and Human Services
  4. SELECTIVE DOPAMINE D-1 AND D-2 FLUORESCENT PROBES

    Amount: $225,602.00

    DYSFUNCTION OF DOPAMINE SYSTEMS IN THE BRAIN HAVE BEEN IMPLICATED IN ENDOCRINE, NEUROLOGICAL AND PSYCHIATRIC DISORDERS, AND DOPAMINERGIC DRUGS ARE WIDELY PRESCRIBED FOR THESE DISORDERS. BRAIN DOPAMINE ...

    SBIR Phase II 1989 National Science Foundation
  5. SYNTHESIS OF FLUORESCENT PROBES FOR MONITORING BRAIN RECEPTOR MOBILITY

    Amount: $500,000.00

    DYSFUNCTION OF DOPAMINE SYSTEMS IN THE BRAIN HAVE BEEN IMPLICATED IN ENDOCRINE, NEUROLOGICAL AND PSYCHIATRIC DISORDERS, AND DOPAMINERGIC DRUGS ARE WIDELY PRESCRIBED FOR THESE DISORDERS. BRAIN DOPAMINE ...

    SBIR Phase II 1989 Department of Health and Human Services
  6. FLUORESCENT PROBES FOR BRAIN SEROTONIN RECEPTORS

    Amount: $437,288.00

    DYSFUNCTION OF SEROTONINERGIC (5HT) SYSTEMS IN THE BRAIN HAVE BEEN IMPLICATED IN NEUROLOGICAL AND PSYCHIATRIC CONDITIONS. DRUGS THAT INTERACT WITH BRAIN 5HT1A RECEPTORS ARE EFFECTIVE IN RELIEVING ANXI ...

    SBIR Phase II 1991 Department of Health and Human Services
  7. AFFINITY LABELS FOR DOPAMINE RECEPTORS

    Amount: $393,816.00

    DYSFUNCTION OF BRAIN DOPAMINE (DA) RECEPTORS HAS BEEN IMPLICATED IN ENDOCRINE, NEUROLOGICAL, AND PSYCHIATRIC DISORDERS. DETAILED PHARMACOLOGICAL EVALUATION AND THE STUDY OF BIOCHEMICAL FUNCTION OF THE ...

    SBIR Phase II 1990 Department of Health and Human Services
  8. BORON-CONTAINING ISOQUINOLINES AND BENZOIDIAZEPINES FOR TARGETING GLIOMA CELLS

    Amount: $50,000.00

    BORON NEUTRON-CAPTURE THERAPY (BNCT) IS A BINARY SYSTEM FOR DELIVERING INTENSELY IONIZING RADIATION TO TUMORS USING A COMBINATION OF BORON-10 LABELED MOLECULES AND THERMAL NEUTRONS TO ACHIEVE A TUMORC ...

    SBIR Phase I 1989 Department of Energy
  9. PROBES OF THE IMIDAZOLINE/GUANIDINIUM RECEPTOR

    Amount: $500,000.00

    THE OBJECTIVE OF THIS PROJECT IS THE SYNTHESIS AND UTILIZATION OF FUNCTIONALIZED MOLECULAR PROBES SPECIFIC FOR THE IMIDAZOLINE/GUANIDINIUM RECEPTIVE SITE (IGRS), A POTENTIAL IMPORTANT RECEPTOR INVOLVE ...

    SBIR Phase II 1993 Department of Health and Human Services
  10. PET AND SPECT IMAGING OF THE DOPAMINERGIC SYSTEM

    Amount: $540,108.00

    THIS APPLICATION DESCRIBES A COLLABORATIVE PROGRAM TO DEVELOP NON-INVASIVE TOOLS FOR THE STUDY OF THE MOLECULAR AND BIOCHEMICAL MECHANISMS OF CENTRAL DOPAMINERGIC NEUROTRANSMISSION. THE PRIMARY NEUROC ...

    SBIR Phase II 1994 Department of Health and Human Services

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