RADIOLABELED ANTIBODY DELIVERY SYSTEM QUALITY CONTROL

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$482,000.00
Award Year:
1989
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Agency Tracking Number:
4776
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Rhomed Inc.
1104 Stanford Drive Northeast, Albuquerque, NM, 87106
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Buck A Rhodes
Principal Investigator
(505) 256-0595
Business Contact:
() -
Research Institution:
n/a
Abstract
A QUALITY CONTROL (QC) TEST KIT WILL BE DEVELOPED AND AND VALIDATED FOR USE IN MEASURING THE PERCENTAGE OF IMMUNOREACTIVE RADIOACTIVITY OF RADIOLABELED ANTIBODY OR ANTIBODY FRAGMENTS INTENDED FOR PATIENT USE. THIS QC PRODUCT IS BEING DESIGNED FOR A MULTICENTERED CLINICAL TRIALOF COMPOUNDED, RADIOLABELED ANTIBODIES. PANELS OF CURRENTLYAVAILABLE MONOCLONAL ANTIBODIES (MABS) THAT HAVE POTENTIAL FOR TARGETING DRUGS AND RADIOISOTOPES TO TUMORS WILL BE SELECTED FOR INCLUSION IN THE CLINICAL TRIAL. THIS PRODUCT WILL BE USED IN AN ANTIBODY DELIVERY SYSTEM, WHICH WILL EMPLOY A MONOCLONAL ANTIBODY/TUMOR-ASSOCIATED ANTIGEN (MAB/TAA) MATCHING KIT TO SELECT ANTIBODIES FOR USE IN INDIVIDUAL PATIENTS. THE QC TEST RESULTS WILL BE USED TO DETERMINE ACCEPTABILITY OF THE COMPOUNDED DRUG FOR PATIENT USE AND FOR POOLING OF DATA FROM DIFFERENT INSTITUTIONS.

* information listed above is at the time of submission.

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