Continuous Cardiac Output Determination
Small Business Information
Rocky Mountain Research, Inc.
2715 East 3300 South, Salt Lake City, UT, 84109
AbstractThermal dilution, the most common method used for determining cardiac output, is highlytechnique dependant and yields results that may be off as much as +/- 2O%. To reduce error, theprocedure is often repeated a number of times and the average of all of the readings taken. Each readingrequires a bolus injection of solution, increasing the risk of sepsis and fluid overload. Modifications tothis technique using intravascular heating elements as the thermal indicator offer nearly continuousreadings but no better accuracy. A continuous cardiac output catheter will use the arterial pressure tocalculate cardiac output. The significant difference to the approach described is a method by which thesystem may be calibrated without injection of any sort of indicator. As a result, the calibration may berepeated as often as desired with no adverse effect to the patient. The phase I studies are designed toconclusively demonstrate the feasibility of the calibration method first using a mock circulation and thana number of animal experiments to validate the data. Phase II would be directed towards productdevelopment and FDA clearance for the device.
* information listed above is at the time of submission.