THE LONG-TERM OBJECTIVE OF THIS PROPOSED RESEARCH IS TO OFFER TO HOSPITALS AND LARGE GROUP PRACTICES A FAST, ACCURATE, SAFE, PAINLESS, AND INEXPENSIVE DEVICE FOR DIAGNOSING CYSTIC FIBROSIS IN PATIENTS OF ANY AGE.

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 1534
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1984
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
800 Eastowne Drive, Suite 209, Chapel Hill, NC, 27514
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 WILLIAMS T. JOINES
 DIRECTOR
 () -
Business Contact
Phone: () -
Research Institution
N/A
Abstract
THE LONG-TERM OBJECTIVE OF THIS PROPOSED RESEARCH IS TO OFFER TO HOSPITALS AND LARGE GROUP PRACTICES A FAST, ACCURATE, SAFE, PAINLESS, AND INEXPENSIVE DEVICE FOR DIAGNOSING CYSTIC FIBROSIS IN PATIENTS OF ANY AGE. OUR TECHNIQUE IS SPECTROSCOPIC IN SITU ANALYSIS OF SWEAT. PHASE I OF OUR RESEARCH PLAN IS INTENDED TO PRODUCE A CLINICAL PROTOTYPE OF OUR DEVICE. THIS RESEARCH PLAN IS AN OUTGROWTH OF EARLIER RESEARCH WHICH PRODUCED THE GOVERNING THEORY AND LABORATORY EQUIPMENT. PHASE I OBJECTIVES INCLUDE THE OPTIMIZATION OF OUR TECHNIQUE AND EQUIPMENT, AND THE RESOLUTION OF REMAINING QUESTIONS. THE SPECIFIC AIMS OF PHASE I RESEARCH ARE THE DEVELOPMENT OF AN OPTIMIZED POWER SUPPLY, PHOTOMULTIPLIER DETECTOR, COMPUTER CONTROL SYSTEM, GLASS ELECTRODE, PORTABLE CART, AND THE CHEMICAL ANALYSIS OF SWEAT INDUCED BY THE SYSTEM. AFTER PHASE I RESEARCH IS COMPLETED AND A CLINICAL PROTOTYPE IS PRODUCED, A CLINICAL TESTING PERIOD WILL FOLLOW UNDER A SEPARATE RESEARCH AGENDA. THE RESULTS OF THIS TESTING WILL PROVIDE THE BASIS FOR PHASE II WORK. PHASE II RESEARCH AND DEVELOPMENT WILL RESULT IN A COMMERCIAL VERSION OF THE IN SITU SPECTROSCOPIC DEVICE WHICH WILL THEN BE OFFERED TO HOSPITALS AND GROUP PRACTICES FOR THE ROUTINE SCREENING AND DIAGNOSIS OF CYSTIC FIBROSIS.

* Information listed above is at the time of submission. *

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