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AN ULTRA-COMPACT N-13 AMMONIA GENERATOR FOR PET

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 19344
Amount: $599,608.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 1994
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
15 Ward Street
Somerville, MA 02143
United States
DUNS: N/A
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Rita E Shefer
 (617) 547-1122
Business Contact
Phone: () -
Research Institution
N/A
Abstract

THE OBJECTIVE OF THIS PROGRAM IS TO DEVELOP A DEDICATED, ACCELERATOR-BASED (13)N-AMMONIA DELIVERY SYSTEM FOR POSITRON EMISSION TOMOGRAPHY (PET). (13)N-AMMONIA PET SCANS CAN ACCURATELY MEASURE MYOCARDIAL BLOOD FLOW AND HAVE BEEN SHOWN TO BE VALUABLE TOOLS IN DIAGNOSING CORONARY ARTERY DISEASE. (13)N-AMMONIA CAN ALSO BE UTILIZED TO MEASURE BLOOD FLOW IN OTHER PARTS OF THE BODY, INCLUDING THE LIVER, KIDNEY, BRAIN AND MALIGNANT TUMORS. THE GENERATOR WILL UTILIZE A VERY LOW ENERGY COAXIAL CASCADE ACCELERATOR (CCA) DEVELOPED AT SRL TO PRODUCE (13)N VIA THE (12)C(D,N)(13)N NUCLEAR REACTION. THE FULLY SHIELDED ACCELERATORY AND (13)N-AMMONIA PRODUCTION SYSTEM WILL BE HOUSED IN A 1.8 M X 1 M X 1.2 M ENCLOSURE AND WILL BE FULLY AUTOMATED WITH EASILY OPERATED PUSH-BOTTON CONTROLS. THE ESTIMATED COST OF THE (13)N-AMMONIA DELIVERY SYSTEM IS COMPARABLE TO THAT OF A ONE OF A ONE YEAR SUPPLY OF (82)RB, ANOTHER COMMONLY USED BLOOD FLOW AGENT.

* Information listed above is at the time of submission. *

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