ENZYMATIC LUMINESCENCE microRNA ASSAY

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1R43CA126647-01
Agency Tracking Number: CA126647
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2007
Solicitation Year: 2007
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
10425 COGDILL RD., #300, KNOXVILLE, TN, 37932
DUNS: 015180610
HUBZone Owned: N
Woman Owned: Y
Socially and Economically Disadvantaged: Y
Principal Investigator
 YE SUN
 (865) 671-2166
 YE_SUN@SCIEN-TEC.COM
Business Contact
 YE SUN
Phone: (865) 671-2166
Email: ye_sun@scien-tec.com
Research Institution
N/A
Abstract
DESCRIPTION (provided by applicant): The goal of this project is to develop a new, highly sensitive, and cost-effective RNA Enzymatic Luminescence Assay (qELA) for high-throughput detection and quantification of microRNA in biological samples. The assay implements the same detection concept known from pyrosequencing, yet expands pyrosequencing detection methodology for highly sensitive and accurate quantification of small RNA molecules. The proposed assay has unique sensitivity and dynamic range and is expected to outperform real-time PCR in applications for analysis of small RNA molecules. The qELA requires less expensive reagents and equipment than RT-PCR and microarrays and can be used in a number of commercial assays for application in life sciences research, drug discovery, and clinical diagnosis.

* Information listed above is at the time of submission. *

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