Cryptosporidosis--A Bioluminescent Cryptosporidium Assay

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$92,972.00
Award Year:
1995
Program:
SBIR
Phase:
Phase I
Contract:
1 R43 AI38689-01,
Award Id:
29144
Agency Tracking Number:
29144
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
187 Ben Burton Circle, Bogart, GA, 30622
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
David Smith
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
There has been a recent concern raised regarding the contamination of water supplies by CryptosporiThis was sparked by the outbreak that occurred in Milwaukee. While contamination by any microbial agCryptosporidium has received much attention, in part, because it is a problem for immunocompromisedthose with AIDS. Current methods of diagnosing cryptosporidiosis in humans is based on the detectionMore recently immunofluorescent test have provided increased sensitivity, but it is dependent on traexpensive equipment i.e., fluorescent microscope. The development of a simple, economical highly senimmunoassay for the detection and quantification of Cryptosporidium oocysts in both clinical and envthe subject of this proposal. This is to be accomplished using monoclonal antibodies specific for thproprietary bioluminescent detection system. The bioluminescent label is based on Aqualite technologphotoprotein which when conjugated with antibodies results in highly sensitive bioluminescent detectbeen successfully applied to a number of clinical assays.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government