SBIR Phase I: Automated Analysis of Body Fluid Chemistry Using MHD-Based Microfluidics

Award Information
Agency: National Science Foundation
Branch: N/A
Contract: 0611074
Agency Tracking Number: 0611074
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2006
Solicitation Year: 2005
Solicitation Topic Code: BT
Solicitation Number: NSF 05-605
Small Business Information
535 West Research Blvd., Fayetteville, AR, 72701
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Prabhu Arumugam
 (479) 571-2592
Business Contact
 Mark Wagstaff
Title: Mr
Phone: (479) 571-2592
Research Institution
This Small Business Innovation Research (SBIR)Phase I project proposes to develop a portable, sealed, self-contained laboratory-on-a-chip using magnetohydrodynamic (MHD) based microfluidic technology to perform chemical analyses of body fluids. These labs-on-a-chip are small, lightweight, consume minimal reagents and power and can be preprogrammed to automate most of the functions of the device such as pumping, mixing, separation and detection. This innovative MHD pumping technology will be integrated with a self-contained microelectrochemical immunoassay detection method for the development of a sealed, fully automated and adaptable lab analysis system for standalone and point-of-care detection applications. The rapid, simultaneous assessment of proteins, lipids, hormones, carbohydrates, vitamins and clinical drugs in blood (or other body fluids) is feasible. The broader impact of this rapid, automated detection device for quantitation of blood chemistry components would allow the health status of a patient to be determined within a single trip to the doctors office or hospital. Any necessary therapeutic measures could begin immediately. Specific examples include the frequent monitoring of hormone levels for diagnosis and control of premenopausal or menopausal symptoms, monitoring of the health of a pregnancy, diagnosis and control of thyroid and pituitary disorders or other hormone regulation systems.

* Information listed above is at the time of submission. *

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