Electrostatic, Non-Fluorescent, Fluctuation Enhanced, Bacterium Spore Analyzer

Award Information
Agency: Department of Defense
Branch: Office for Chemical and Biological Defense
Contract: W911SR-09-C-0032
Agency Tracking Number: C091-109-0053
Amount: $69,999.00
Phase: Phase I
Program: SBIR
Awards Year: 2009
Solicitation Year: 2009
Solicitation Topic Code: CBD09-109
Solicitation Number: 2009.1
Small Business Information
13619 Valley Oak Circle, ROCKVILLE, MD, 20850
DUNS: 620282256
HUBZone Owned: N
Woman Owned: Y
Socially and Economically Disadvantaged: Y
Principal Investigator
 Chiman Kwan
 Chief Technology Officer
 (240) 505-2641
Business Contact
 Chihwa Yung
Title: President
Phone: (301) 315-2322
Email: chihwa.yung@signalpro.net
Research Institution
This SBIR project, by utilizing the principle of Fluctuation-Enhanced Sensing (FES), aims to explore the potential of enhancing the sensitivity and selectivity of electrostatic bacterium spore analyzers, specifically Ion Mobility Spectrometers (IMS) and Mass Spectrometers (MS). We propose a high performance framework that incorporates FES to enhance the detection and classification of bio-aerosols. There are several key components in our system. First, for IMS and MS, different theoretical noise analysis techniques will be applied to analyze noise behavior in different sensors. These theoretical analyses will provide critical information on the sensing limits of different sensors. Second, a library of signal processing/pattern recognition tools will be incorporated to further enhance the detection and classification capability of our framework. We will use a low noise amplifier to enlarge the small stochastic fluctuations in the sensor. Features such as mean-square fluctuations, skewness, kurtosis, power spectrum, zero-crossing patterns, bispectrum images of the fluctuations will be extracted. Various advanced and proven classification algorithms will be used for different features. Finally, we will feed the decisions from different classifiers into a fusion algorithm. A single decision will be drawn, which is robust and optimal, as all information has been taken into account.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government