Advanced Development for Defense Science and Technology

Award Information
Agency: Department of Defense
Branch: Defense Advanced Research Projects Agency
Contract: W31P4Q-08-C-0026
Agency Tracking Number: 07SB2-0096
Amount: $99,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2007
Solicitation Year: 2007
Solicitation Topic Code: SB072-006
Solicitation Number: 2007.2
Small Business Information
1570 Pacheco Street, Suite E-11, Santa Fe, NM, 87505
DUNS: 153579891
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 David Bomse
 Principal Research Scientist
 (505) 984-1322
Business Contact
 Alan Stanton
Title: President
Phone: (505) 984-1322
Research Institution
Southwest Sciences proposes the development of an ultra-sensitive optical spectroscopy technique having applications in explosives and chemical agent detection, and rapid health screening/monitoring for warfighter field diagnostics and health care. The technique, called noise-immune, cavity-enhanced optical heterodyne spectroscopy (NICE-OHMS), was invented about 10 years ago, but has remained a research laboratory technique. It was considered too complex for commercial development. We plan to take advantage of recent improvements in enabling technologies to make NICE-OHMS a reliable, field-rugged, and portable method. If successful, we anticipate two- to four-orders of magnitude sensitivity improvement over competing spectroscopic methods at only modestly higher expense. The proposed technology has numerous military and commercial applications. Our approach starts with the detection of ultra-trace (part per billion, or lower concentrations) gases in exhaled breath that are markers for disease and injury. This application has both military and civilian uses. Obvious target compounds include nitric oxide, acetone which is a marker for diabetes and ketosis, ethylene as an indicator for radiation exposure, ethane and higher alkanes as markers for lipid damage, and dimethyl sulfide for kidney function. In addition, numerous metabolic tests involve ingestion of 13C-labeled compounds followed by time-resolved, high precision measurements of 13CO2/12CO2 changes.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government