Microfluidic Multichannel Flow Cytometer

Award Information
Agency:
National Aeronautics and Space Administration
Branch
n/a
Amount:
$99,958.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
NNX09CE43P
Award Id:
90740
Agency Tracking Number:
084605
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
7200 Highway 150, Greenville, IN, 47124
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
621970383
Principal Investigator:
Paul Todd, Ph. D.
Principal Investigator
(812) 923-9591
ptodd@techshot.com
Business Contact:
Mark Deuser
Business Official
(812) 923-9591
mdeuser@techshot.com
Research Institute:
n/a
Abstract
The proposed innovation is a "Microfluidic Multichannel Flow Cytometer." Several novel concepts are integrated to produce the final design, which is compatible with on-orbit operation from the standpoint of gravity-independence, low mass, low power requirement and automated operation. The unique design features of the Microfluidic Multichannel Flow Cytometer include compact optics based on diode technology for both illumination and measurement, tested channel branching schemes, no sheath fluid anywhere, bubble-free PDMS lithographic manufacture, and analysis based on quantum-dot technology. A design is proposed that counts RBC, WBC and three specified WBC subsets. Techshot, Inc. and scientists at Purdue University will collaborate to test the components of this innovation by pursuing the following Phase I objectives: (1) create a critical design requirements document for the Microfluidic Multichannel Flow Cytometer, (2) breadboard and test its three critical physical components (illumination, sensing optics and flow channels) and (3) critically test feasibility of each component and produce a top-level drawing suitable for initiating Phase II R/R&D to produce an integrated prototype. The final product will be robust for use in space flight and low-cost on Earth for eventual point-of-care blood analysis and global AIDS patient status monitoring.

* information listed above is at the time of submission.

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