REDUCTION OF POLYETHYLENE WEAR IN SURGICAL IMPLANTS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$44,768.00
Award Year:
1990
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
13689
Agency Tracking Number:
13689
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Spire Corp (Currently Spire Corporation)
Patriots Park, Bedford, MA, 01730
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Piran Sioshansi
(617) 275-6000
Business Contact:
() -
Research Institution:
n/a
Abstract
THE COBALT-CHROMIUM-MOLYBDENUM ALLOY DESIGNATED STANDARD SPECIFICATION F-75 BY THE AMERICAN SOCIETY FOR TESTING AND MATERIALS IS THE MOST COMMONLY USED ALLOY IN ORTHOPEDIC PROSTHESES FOR TOTAL AND PARTIAL JOINT REPLACEMENT. THE F-75 ALLOY IS HARD, STABLE, AND CORROSION RESISTANT. ITS WEAR IN JOINT REPLACEMENT PROSTHESES IS NOT A PROBLEM PER SE. HOWEVER, WEAR OF THE MATING ULTRAHIGH-MOLECULAR-WEIGHT POLYETHYLENE (UHMWPE) ON WHICH THE METALLIC PART ARTICULATESIS A WELL-DOCUMENTED CHRONIC PROBLEM. A NUMBER OF RECENT PUBLICATIONS HAVE REPORTED THAT UHMWPE WEAR DEBRIS IS OBSERVED IN THE INTERFACE BETWEEN THE HIP STEM AND FEMOR IN CEMENTED TOTAL HIP REPLACEMENT. THE UHMWPE WEAR DEBRIS IS, THEREFORE, PARTIALLY BLAMED FOR BONE DESORPTION AND EVENTUAL LOOSENING OF THE F-75 ALLOY FEMORAL COMPONENT. ION IMPLANTATION IS AN INNOVATIVE SURFACE MODIFICATION PROCESS THAT CAN READILY BE APPLIED TO FINISHED F-75 ALLOY PROSTHESES. PRELIMINARY RESEARCH AT SPIRE CORPORATION HAS SHOWN THAT ION IMPLANTATION OF BIOLOGICALLY INERT SPECIES SUCH AS NITROGEN AND CARBON INCREASES HARDNESS AND REDUCES THE FRICTION OF THE F-75 ALLOY. THE HARDER, MORE LUBRICIOUSF-75 ALLOY IS EXPECTED TO SIGNIFICANTLY REDUCE WEAR OF THE UHMWPE COMPONENT.

* information listed above is at the time of submission.

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